Manufacturer: Cadila Pharmaceuticals Ltd
Salt Composition : Diclofenac(50mg), Serratiopeptidase(10mg)
Pepzen D 50 mg/10 mg Tablet can be taken with or without food. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
The most common side effects of this medicine include nausea, vomiting, heartburn, stomach pain, indigestion, diarrhea, and loss of appetite. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.
Pepzen D 50 mg/10 mg Tablet is a combination of two medicines: Diclofenac and Serratiopeptidase. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation and promotes healing.
Pharmacokinetics. After oral/IM or rectal administration, Diclofenac sodium + Serratiopeptidase is rapidly absorbed in the GIT. However, the absorption rate is very slow in enteric-coated formulations. The drug can enter breast milk and synovial fluid after distribution.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pepzen D
Nausea
Vomiting
Heartburn
Stomach pain
Indigestion
Diarrhea
Loss of appetite
Diclofenac sodium + Serratiopeptidase is contraindicated in patients with active GI bleeding or perforations, asthma, renal or hepatic disorders, hypertension, porphyria, peri-operative pain in CABG surgery patients and bleeding disorders.
Pepzen D 50 mg/10 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Pepzen D 50 mg/10 mg Tablet.
Information regarding the use of Pepzen D 50 mg/10 mg Tablet during breastfeeding is not available. Please consult your doctor.
Diclofenac / Serratiopeptidase Tablet is a Tablet manufactured by Jan Aushadhi. It is commonly used for the diagnosis or treatment of Sprins, Bone fracture, Dental fracture, Dental surgeries, Lower back pain. It has some side effects such as Epigastric pain, Renal dysfunction, Stomach ulcer, Bleeding.
Drug-Drug Interaction: DICLOFENAC SODIUM+SERRATIOPEPTIDASE may interact with painkillers (nimesulide, oxyphenbutazone, metamizole), anti-cancer (methotrexate), lithium, iodine, and blood clotting agents (warfarin).
Drug-Food Interaction: Drinking alcohol should be avoided while taking DICLOFENAC SODIUM+SERRATIOPEPTIDASE as it can cause unpleasant effects.
Drug-Disease Interaction: People with peptic ulcer, gastric bleeding, severe heart failure, stroke, ulcerative colitis, Crohn's disease, alcoholism, and high blood pressure should avoid intake of DICLOFENAC SODIUM+SERRATIOPEPTIDASE.
Do not chew, crush or break it. Pepzen D 50 mg/10 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Pepzen D 50 mg/10 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
This combination medicine helps relieve pain and inflammation.
Take it with food to avoid getting an upset stomach.
Take it as per the dose and duration prescribed by your doctor.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Pepzen D 50 mg/10 mg Tablet affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pepzen D 50 mg/10 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Pepzen D 50 mg/10 mg Tablet?
Pepzen D 50 mg/10 mg Tablet is a combination of two medicines: Diclofenac and Serratiopeptidase. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
Q. Is it safe to use Pepzen D 50 mg/10 mg Tablet?
Yes, Pepzen D 50 mg/10 mg Tablet is safe for most of the patients. However, in some patients it may cause common unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor as soon as possible if you experience any persistent problem due to the medication.
Q. Can I stop taking Pepzen D 50 mg/10 mg Tablet when my pain is relieved?
Pepzen D 50 mg/10 mg Tablet is usually used for short term and can be discontinued when the pain is relieved. However, Pepzen D 50 mg/10 mg Tablet should be continued if your physician has advised you to do so.
Q. Can the use of Pepzen D 50 mg/10 mg Tablet cause nausea and vomiting?
Yes, the use of Pepzen D 50 mg/10 mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to a doctor.
