Phosmid 500mg (Injection)

Manufacturer: Neon Laboratories Ltd

Salt Composition : Cyclophosphamide(500mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

₹43.00

Vial of 1 Injection

(Inclusive of all taxes)


Phosmid 500mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Basic Information

Mechanism Of Action

Cyclophosphamide is an alkylating agent of the nitrogen mustard type. 2 An activated form of cyclophosphamide, phosphoramide mustard, alkylates, or binds, to DNA. Its cytotoxic effect is mainly due to cross-linking of strands of DNA and RNA, and to inhibition of protein synthesis

Pharmacokinets

Cyclophosphamide is inactive until it undergoes hepatic transformation to form 4-hydroxycyclophosphamide, which then breaks down to form the ultimate alkylating agent, phosphoramide mustard.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Phosmid

Vomiting

Nausea

Hair loss

Fever

Blood in urine

Diarrhea

Decreased white blood cell count (neutrophils)

Contra Indications

a bacterial infection.

chickenpox.

shingles.

opportunistic fungal infection.

an infection due to a protozoa organism.

an infection due to a parasite.

myeloproliferative neoplasm.

low amount of sodium in the blood

Pregnancy Related Information

Phosmid 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Phosmid 500mg Injection.


Breast Feeding Related Information

Phosmid 500mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Cyclophosphamide is indicated for the treatment of biopsy proven minimal change nephrotic syndrome in pediatrics patients who failed to adequately respond to or are unable to tolerate adrenocorticosteroid therapy

Interactions

adenovirus types 4 and 7 live, oral.

carbamazepine.

etanercept.

hydrochlorothiazide.

idarubicin.

idelalisib.

influenza virus vaccine trivalent, adjuvanted.

ivacaftor.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.

Effects Of Missed Dosage

If you miss a dose of Phosmid 500mg Injection, please consult your doctor.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Phosmid 500mg Injection helps in the treatment of cancer.

It is injected into the vein by a doctor or healthcare professional.

Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.

Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.

You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.

Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.

Do not take Phosmid 500mg Injection if you are pregnant or breastfeeding.

Use effective contraception method to prevent pregnancy while taking this medicine.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. Can Phosmid 500mg Injection cause infertility?

Yes, Phosmid 500mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Phosmid 500mg Injection.

Q. Do I need to avoid sun exposure during treatment with Phosmid 500mg Injection?

No, there is no evidence that you need to avoid sun exposure while on Phosmid 500mg Injection. Skin and nail discoloration are reported rarely with Phosmid 500mg Injection.

Q. Can Phosmid 500mg Injection cause cancer?

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Phosmid 500mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Phosmid 500mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

Q. Is Phosmid 500mg Injection chemotherapy medicine?

Yes, Phosmid 500mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.

Q. Can Phosmid 500mg Injection be used for non-cancer condition?

Yes, Phosmid 500mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Phosmid 500mg Injection for nephrotic syndrome has not been established.

Q. Can Phosmid 500mg Injection causes weight loss?

Yes, Phosmid 500mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.