Picon 1% Lotion

Manufacturer: Biocon

Salt Composition : Pimecrolimus(1% w/w)


Picon Lotion is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.


It is a safe medicine with few side effects, but you may get an application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.


Basic Information

Mechanism Of Action

Picon Lotion is an immunosuppressant. It works by suppressing your body’s immune response.

Pharmacokinets

Also, pimecrolimus prevents the release of inflammatory cytokines and mediators from mast cells in vitro after stimulation by antigen/lgE. Because of the low systemic absorption of pimecrolimus following topical application the calculation of standard pharmacokinetic measures such as AUC, Cmax, half-life, etc.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Picon

Application site reactions (burning, irritation, itching and redness)

Contra Indications

Patients who are immunocompromised or are taking systemic immunosuppressive medications.

Areas of skin with active pre-malignant or malignant lesions (such as cutaneous T-cell lymphoma (CTCL)) or skin infections (bacterial or viral)

Pregnancy Related Information

Picon Lotion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Product And Alcohol Interaction

No interaction found/established

Breast Feeding Related Information

Picon Lotion is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Indications

Mild to severe atopic dermatitis in patients under 2 years of age[1][2]

Eczematous dermatitis of the eyelids,[3] intertriginous (skin fold) areas, or hands[4]

Facial and inverse psoriasis[5]

Oral and genital lichen planus[6][7]

Lichen sclerosis[8]

Seborrheic dermatitis[9]

Perioral dermatitis[10]

Vitiligo[11]

Interactions

Drug-Drug Interaction: PIMECROLIMUS may interact with antifungals (fluconazole, itraconazole, ketoconazole), calcium channel blockers (diltiazem, verapamil), antiulcer (cimetidine) antibiotics (clarithromycin, erythromycin, troleandomycin, metronidazole), androgenic hormones (danazol), immunosuppressant (cyclosporine), HIV protease inhibitors (indinavir, ritonavir, delavirdine), anti-TB (isoniazid), an antidepressant (nefazodone, fluoxetine, fluvoxamine), oral contraceptives (birth control pills).

Drug-Food Interaction: PIMECROLIMUS may interact with alcohol. Therefore, avoid the consumption of alcohol with PIMECROLIMUS.

Drug-Disease Interaction: If you have skin areas that have cancers or pre-cancers, Netherton's syndrome, skin infections (including chickenpox or herpes), or a weak immune system, inform your doctor before taking PIMECROLIMUS.

Drug-Drug Interactions Checker List:

FLUCONAZOLE

ITRACONAZOLE

KETOCONAZOLE

DILTIAZEM

VERAPAMIL

CIMETIDINE

CLARITHROMYCIN

ERYTHROMYCIN

TROLEANDOMYCIN

METRONIDAZOLE

DANAZOL

CYCLOSPORINE

INDINAVIR

RITONAVIR

DELAVIRDINE

ISONIAZID

NEFAZODONE

FLUOXETINE

FLUVOXAMINE

Typical Dosage

Shake it well and apply to the area evenly.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Picon Lotion is effective at treating eczema (atopic dermatitis) when other treatment options have failed.

Apply thinly, to affected areas of skin only. Clean the affected area and dry well before applying Picon Lotion. Avoid contact with water (shower, swimming) right after application.

Clean the area to be treated with water and a non-medicated soap, and let it dry completely before applying Picon Lotion.

Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.

Inform your doctor if there's no improvement even after two weeks of treatment, or if the skin gets worse.

Stop using Picon Lotion and consult your doctor if your eczema becomes infected.

Continuous long-term use of the ointment should be avoided. Use as prescribed by you doctor.

How To Use

This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

FAQs

Q. Is Picon Lotion a steroid?

No. Picon Lotion is an immuno-suppressant. It is not a steroid.

Q. Is Picon Lotion effective?

Yes, Picon Lotion is effective if used in the dose and duration advised by your doctor. Do not stop using it even if you see improvement in your condition. If you stop using Picon Lotion too early, the symptoms may return or worsen.

Q. Is Picon Lotion available over the counter?

No, it is not an over the counter medicine. Picon Lotion is a prescription medicine which means that it can be bought only with a valid prescription by a doctor.

Q. What is Picon Lotion used for?

Picon Lotion is used for treating mild or moderate atopic dermatitis (eczema) of the skin, in cases where corticosteroids cannot be used.