Manufacturer: Systopic Laboratories Pvt Ltd
Salt Composition : Pioglitazone(15mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Pio 15mg Tablet may be used by itself or along with other medicines. It may be taken with or without food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.
Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of taking this medicine include weight gain, blurred vision, and numbness. Please consult your doctor if these bother you or persist for a longer duration.
You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.
Pioglitazone improves glycaemic control in people with Type 2 diabetes by improving insulin sensitivity through its action at PPAR gamma 1 and PPAR gamma 2, and affects lipid metabolism through action at PPAR alpha.
Serum concentrations of total pioglitazone (pioglitazone plus active metabolites) remain elevated 24 hours after once daily dosing. Steady-state serum concentrations of both pioglitazone and total pioglitazone are achieved within 7 days.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pio
Hypoglycemia (low blood glucose level)
Edema (swelling)
Upper respiratory tract infection
Bronchitis (inflammation of the airways)
Anemia (low number of red blood cells)
Patients with a known hypersensitivity to pioglitazone or any of its components.
Diabetic ketoacidosis or type 1 diabetes, since pioglitazone is active only in the presence of insulin.
Hypoglycemia, therefore, regular blood sugar monitoring is imperative.
Pio 15mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Pio 15mg Tablet.
Pio 15mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Monitor the breastfed baby’s blood sugar during treatment with Pio 15mg Tablet
Pioglitazone is used with a diet and exercise program and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Pioglitazone is in a class of medications called thiazolidinediones.
Pioglitazone is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated).
Do not chew, crush or break it. Pio 15mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Pio 15mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Pio 15mg Tablet helps to control blood sugar level and avoid long-term complications.
Take it only as per dose and duration suggested by your doctor.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Pio 15mg Tablet.
Full effects may be visible after several weeks of starting Pio 15mg Tablet. Keep taking it as prescribed by your doctor.
Monitor your blood sugar level regularly while taking this medicine.
Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pio 15mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can Pio 15mg Tablet cause weight gain?
Pio 15mg Tablet commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.
Q. Can Pio 15mg Tablet cause heart failure?
Pio 15mg Tablet can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Pio 15mg Tablet is used with insulin.
Q. Can you take Pio 15mg Tablet and metformin together?
Yes, Pio 15mg Tablet can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.
Q. What time of day should you take Pio 15mg Tablet?
It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Pio 15mg Tablet exactly as prescribed by your doctor.