Manufacturer: Cipla Ltd
Salt Composition : Pirfenidone(600mg)
Pirfenex 600mg Tablet is best taken with food. Take it at the same time every day to get the most benefits. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.
The most common side effects of this medicine include insomnia, headache, dizziness, dyspepsia, nausea, diarrhea, and photosensitivity. To overcome dizziness, avoid driving or attention-seeking activity. Some people may experience weight loss and other side effects. Monitor your weight regularly or ask for the doctor's advice in such cases. Your doctor also may perform a liver function test while on treatment with this medicine.
Before taking this medicine, let your doctor know if you have liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. It makes your skin sun-sensitive, wear protective clothing or apply sunscreen while in direct contact with the sun. Inform your doctor if you are pregnant or breastfeeding.
Pirfenex 600mg Tablet is an antifibrotic medication. It works by blocking the action of a certain natural substance in the body that is involved in causing fibrosis. This reduces the scarring and swelling in the lungs and makes breathing easier.
Within 24 hours, approximately 80% of the pirfenidone dose is excreted mainly in the urine. About 99.6% of the recovered dose of pirfenidone was excreted as the 5-carboxy metabolite. About less than 1% of the dose was excreted as unchanged parent drug and less than 0.1% of the dose was excreted as other metabolites.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pirfenex
Insomnia (difficulty in sleeping)
Headache
Dizziness
Tiredness
Sinus inflammation
Loss of appetite
Upper respiratory tract infection
Weight loss
Nausea
Indigestion
Diarrhea
Photosensitivity
carbamazepine. carbamazepine will decrease the level or effect of pirfenidone by affecting hepatic enzyme CYP1A2 metabolism. ...
phenobarbital. phenobarbital will decrease the level or effect of pirfenidone by affecting hepatic enzyme CYP1A2 metabolism. ...
primidone. ...
rifampin.
Pirfenex 600mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Pirfenex 600mg Tablet. Please consult your doctor.
Information regarding the use of Pirfenex 600mg Tablet during breastfeeding is not available. Please consult your doctor.
Pirfenidone Viatris is used to treat adults with mild to moderate idiopathic pulmonary fibrosis (IPF). IPF is a long-term disease in which fibrous scar tissue continuously forms in the lungs, causing persistent cough, frequent lung infections and severe shortness of breath.
Drug-Drug Interactions: PIRFENIDONE may interact with an anti-depressant (fluvoxamine), antibiotics (ciprofloxacin, enoxacin, rifampicin), antiarrhythmic (amiodarone, propafenone), antacid (omeprazole).
Drug-Food Interactions: Avoid grapefruit juice and chargrilled meats.
Drug-Disease Interactions: Inform your doctor if you have severe hepatic problems or end-stage renal impairment requiring dialysis.
Drug-Drug Interactions Checker List:
FLUVOXAMINE
CIPROFLOXACIN
ENOXACIN
RIFAMPICIN
AMIODARONE
PROPAFENONE
OMEPRAZOLE
Do not chew, crush or break it. Pirfenex 600mg Tablet is to be taken with food.
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
Pirfenex 600mg Tablet reduces scarring and swelling in the lungs, and helps you breathe better.
It is best to take this medicine with food and at the same time each day.
This medication may make you more sensitive to sun. Use sunscreen and wear protective clothing when outdoors.
Stop smoking during treatment with Pirfenex 600mg Tablet as it can reduce the effect of the treatment.
It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
It may cause weight loss. Monitor your weight regularly.
Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pirfenex 600mg Tablet is to be taken with food.
Q. What monitoring will I need during treatment with Pirfenex 600mg Tablet?
Your doctor will check your liver function before starting treatment with Pirfenex 600mg Tablet. This test will be repeated monthly for the first 6 months and then it will be done after every three months. In addition to that, your doctor will also monitor your lung function periodically in order to see the response to Pirfenex 600mg Tablet.
Q. Why is it important to continue treatment with Pirfenex 600mg Tablet?
It is important to control the progression of the disease by preserving your lung function which cannot be restored, once lost. Hence, it is highly recommended to start and continue the treatment with Pirfenex 600mg Tablet as prescribed by your doctor. Doing so can help preserve the existing lung function.
Q. What are the side effects of Pirfenex 600mg Tablet?
Most common side effects of Pirfenex 600mg Tablet include skin sensitivity to sunlight, nausea, tiredness, diarrhea, indigestion or upset stomach, loss of appetite, and headache. Other common side effects include infections of the throat or the airways, bladder infections, weight loss, difficulty sleeping, dizziness, sleepiness, changes in taste, hot flushes, shortness of breath, and cough. Additionally, one may experience stomach problems such as acid reflux, vomiting, bloating, abdominal pain and discomfort, heart burn, constipation, skin problems such as itchy skin, skin redness or red skin, dry skin, skin rash, muscle pain, aching joints/joint pains, weakness, chest pain, and sunburn. It is possible that after using Pirfenex 600mg Tablet blood tests may show increased levels of liver enzymes.
Q. Is Pirfenex 600mg Tablet a steroid?
No, Pirfenex 600mg Tablet is not a steroid. It belongs to pyridines group of medicines. It is used to treat idiopathic pulmonary fibrosis (IPF) in adults. In IPF, the tissues of the lungs get scarred and swell with time, which creates problem in breathing. This medicine helps reduce these effects to make you breathe better.
