Manufacturer: Bharat Serums & Vaccines Ltd
Salt Composition : Albumin(0.05)
Plasmanate 5% Infusion is used to treat blood volume loss. It works by replacing the body fluids lost due to excessive trauma, bleeding, surgery, or kidney dialysis. Thus, it is helpful in treating low blood albumin levels.
Plasmanate 5% Infusion must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergies to this injection. Before taking it, inform the doctor you are suffering from any severe heart disease.
Your doctor may check your blood pressure and ask you to get regular blood tests done while you are using this injection. The most common side effects include flushing, nausea, vomiting, chills, and fever.
Inform your doctor if you are pregnant or breastfeeding. Let your doctor also know if you have any kidney diseases as a dose adjustment may be required. This injection is safe to use in patients suffering from liver diseases.
Albumin has two essential physiologic functions[2]: Contribute to colloid osmotic pressure. Aid in the transportation, distribution, and metabolism of endogenous and exogenous molecules (fatty acids, thyroid hormones, metals, oxide nitric, peptides, and drugs)
The combination of drug and serum albumin plays an essential role in pharmacodynamics and pharmacokinetics of drugs [8]. It is known that the free (unbound) concentration, distribution, and metabolism of various drugs are strongly affected by the combination of drug and albumin in the blood stream
Vomiting
Flushing (sense of warmth in the face, ears, neck and trunk)
Fever
Nausea
Chills
Hives
Slow heart rate
Contraindications include clinical situations that present with volume overloads, such as severe anemia, congestive heart failure, or renal insufficiency, at high risk of hemodynamic instability when treated with albumin solutions
Plasmanate 5% Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Plasmanate 5% Infusion. Please consult your doctor.
Information regarding the use of Plasmanate 5% Infusion during breastfeeding is not available. Please consult your doctor.
Fluid resuscitation (should not be used as first line treatment – use crystalloids first)
Significant hypoalbuminemia.
Nephrotic syndrome.
Therapeutic plasma exchange.
Cardiothoracic surgery as a pump prime for cardiopulmonary bypass.
In addition to oleic acid, they find S-nitrosylated human serum albumin also strongly interacts with Bilirubin and weakly interacts with L-tryptophan, progesterone, ascorbate, Zinc, and iron
Kindly do not self-administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Plasmanate 5% Infusion, please consult your doctor.
Consult a doctor before taking any medicines
It is given as an injection into veins under the supervision of a medical professional.
Inform your doctor immediately if you experience a skin rash, itching, breathing difficulties, swelling of face and changes in heartbeat while using this medicine.
Inform your doctor if you have history of severe anemia (lack of red blood cells), or severe heart failure.
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
Q. What do you need to inform your doctor before you are given Plasmanate 5% Infusion?
Before you are given this medicine, you need to inform your doctor if you are allergic to albumin preparations or to any of the other ingredients of this medicine. Suspicion of allergic or anaphylactic type reactions requires an immediate stop of the infusion.
Q. What vitals should be monitored before giving Plasmanate 5% Infusion
Before giving this injection, your doctor or nurse will measure your blood pressure, and heart rate and conduct blood tests to make sure you are not given an excess dose. If you experience a headache, difficulty in breathing, or increased blood pressure, inform your doctor immediately.
Q. How is Plasmanate 5% Infusion given?
This medicine must be administered intravenously at a rate not to exceed 1 mL/min to patients with normal blood volume, due to the risk of developing circulatory overload and pulmonary edema (excess fluid in lungs).
