Manufacturer: Dr Reddy's Laboratories Ltd
Salt Composition : Becaplermin(100mcg)
Plermin Gel accelerates healing and formation of healthy skin, thus providing relief in the skin infection. It is meant for external use only. You should use it in the dose and duration as advised by your doctor. The affected area should be clean and dry before application of this medicine. You must wash your hands thoroughly before and after applying this medicine. This medicine should be used regularly to get the most benefit from it.
If your condition does not improve or gets worse at any time, let your doctor know. You can help this medication work better by keeping the affected areas clean, making sure they are dry, and washing your hands before and after treating the infection. It is advised to use proper footwear to increase the effectiveness of the medicine.
Some common side effects include burning, irritation, itching, and redness at the site of application. If the side effects bother you or do not go away, let your doctor know. Some people have a severe allergic reaction which needs urgent medical attention. Signs of this include rash, swelling of the lips, throat or face, swallowing or breathing problems, dizziness and nausea. Get emergency help if this happens.
It is not likely that other medicines you take by mouth or injection will affect the way it works but talk to your doctor before using it if you have used a similar medicine before and had an allergic reaction. This medicine should only be used if it is clearly needed during pregnancy.
Plermin Gel works by releasing a growth factor that causes skin regeneration in diabetic foot ulcer.
Pharmacokinetic studies in humans have shown that systemic absorption after topical applications was minimal. In trials, systemic and local tolerance were excellent. Reported adverse effects were similar in incidence and in nature in all groups.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Plermin
Application site reactions (burning, irritation, itching and redness)
(becaplermin) Gel is contraindicated in patients with: − known hypersensitivity to any component of this product (e.g., parabens); − known neoplasm(s) at the site(s) of application. growth factor, which promotes cellular proliferation and angiogenesis.
Plermin Gel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Information regarding the use of Plermin Gel during breastfeeding is not available. Please consult your doctor.
indicated for the treatment of lower extremity diabetic neuropathic ulcers that extend into the subcutaneous tissue or beyond and have an adequate blood supply, when used as an adjunct to, and not a substitute for, good ulcer care practices including initial ...
Drug-Drug Interaction: No interactions found.
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have cancer, skin tumor or poor blood flow to lower legs and feet, please inform your doctor before taking BECAPLERMIN.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Plermin Gel, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Use it as per dose and duration suggested by the doctor.
Make sure that ulcer area is clean properly before applying the medication.
Few tips for good foot care:
Wash your feet properly with lukewarm water and apply moisturizer to prevent cracking.
Wear comfortable shoes and avoid shoes with high heels and pointed toe.
look for cuts, sores, burns, and redness while examining your feet.
Avoid the use of heat pads on the feet.
Make sure to not put pressure on the affected foot while standing or walking.
Dress the ulcer area properly to keep it clean and warm.
Put your feet up and avoid crossed legs while sitting.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
Q. What is Plermin Gel used for?
Plermin Gel is used to treat long standing ulcers of the foot, ankle or legs in diabetic patients
Q. How does Plermin Gel work?
Plermin Gel works by growth and development of cells that repair wounds and help to close and heal the ulcer.
