Manufacturer: Venus Remedies Ltd
Salt Composition : Amikacin(500mg), Cefepime(2000mg)
Potentox 500 mg/2000 mg Injection must be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the medicine should be completed even if you feel better. It may cause mild injection site redness and pain.
The medicine may cause some side effects such as headache, nausea, dizziness, loss of appetite, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.
Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult the doctor about this condition. During the treatment, take proper rest to achieve a faster recovery.
The primary mechanism of action of amikacin is the same as that for all aminoglycosides. It binds to bacterial 30S ribosomal subunits and interferes with mRNA binding and tRNA acceptor sites, interfering with bacterial growth.
Cefepime inhibits bacterial cell wall synthesis by covalently binding enzymes responsible for the final step in transpeptidation during peptidoglycan wall synthesis. This binding causes defects in the cell wall leading to autolysis and subsequent death of the organism.
The plasma elimination half-life of amikacin is usually 2-3 hours in adults with normal renal function and is reported to range from 30-86 hours in adults with severe renal impairment. The mean serum clearance rate is about 100 mL/min and the renal clearance rate is 94 mL/min in subjects with normal renal function,Pharmacokinetic studies indicate that cefepime exhibits linear pharmacokinetic behaviour. Pharmacokinetic variables are not significantly different between single- and multiple-dose administration, indicating a lack of drug accumulation in patients with normal renal function.
Ringing in ear
Hearing loss
Vertigo
Nausea
Vomiting
Abnormal kidney function test
Injection site pain
Injection site reaction
Injection site inflammation
Allergic reaction
Rash
Clostridium difficile infection
Hypersensitivity to amikacin or any other aminoglycoside
Hypersensitivity to cephalosporins, penicillins or other beta-lactam antibiotics
Neurotoxicity caused by drug
Pseudomembranous colitis
Potentox 500 mg/2000 mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Caution is advised when consuming alcohol with Potentox 500 mg/2000 mg Injection. Please consult your doctor.
Potentox 500 mg/2000 mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Avoid prolonged use of Potentox 500 mg/2000 mg Injection, since it may have possible effects such as rash and diarrhea.
Amikacin+Cefepime is used in the treatment of bacterial infections. Amikacin + Cefepime is a combination of two medicines: Amikacin and Cefepime. Amikacin is an antibiotic which stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.
Amikacin
Aminoglycoside antibiotics
Amphotericin B
Bacitracin
Cephaloridine
Cisplatin
Colistin
Diuretics
Ethacrynic acid
Furosemide
Kindly do not self administer.
Store below 30°C
If you miss a dose of Potentox 500 mg/2000 mg Injection , please consult your doctor
Consult a doctor before taking any medicines.
Potentox 500 mg/2000 mg Injection is given as an injection into vein or drip under the supervision of a doctor.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
Your doctor will monitor you regularly for the kidney function, blood urea level and hearing loss during the treatment.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What if I don't get better after using Potentox 500 mg/2000 mg Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. How long does Potentox 500 mg/2000 mg Injection takes to work?
Usually, Potentox 500 mg/2000 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
