Manufacturer: Dr Reddy's Laboratories Ltd
Salt Composition : Apremilast(30mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Pravy 30mg Tablet can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. You may need to monitor your weight regularly while taking the medicine as it may cause weight loss.
Using this medicine may cause few common side effects such as nausea, diarrhea, and vomiting. If these side effects persist or get worse, let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.
Pravy 30mg Tablet is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms of these conditions.
An oral dose of apremilast is well-absorbed and the absolute bioavailability is approximately 73%. Tmax is approximately 2.5 hours 14 and Cmax has been reported to be approximately 584 ng/mL in one pharmacokinetic study. Food intake does not appear to affect apremilast absorption.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pravy
Diarrhea
Nausea
Vomiting
Patients with any known hypersensitivity to apremilast and its constituents are contraindicated for treatment. Apremilast is labeled as pregnancy category C. Women of reproductive potential should be advised about the potential risk of pregnancy loss with apremilast.
Pravy 30mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Pravy 30mg Tablet. Please consult your doctor.
Information regarding the use of Pravy 30mg Tablet during breastfeeding is not available. Please consult your doctor.
Apremilast is indicated for the treatment of adults with active psoriatic arthritis and adults with oral ulcers associated with Behcet's Disease. In addition, apremilast is indicated for the treatment of plaque psoriasis, of any severity, in adult patients who are candidates for phototherapy or systemic therapy.
Drug-Drug Interactions: APREMILAST may interact with medicines used for tuberculosis- TB (rifampicin), and medicines used in fit/epilepsy (phenytoin, phenobarbital, carbamazepine).
Drug-Food Interactions: No food interactions were found.
Drug-Disease Interactions: APREMILAST should not be given to patients with depression, kidney disease, and weight loss.
Drug-Drug Interactions Checker List:
RIFAMPICIN
PHENYTOIN
CARBAMAZEPINE
PHENOBARBITAL
Store below 30°C
If you miss a dose of Pravy 30mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Pravy 30mg Tablet is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
Monitor your weight regularly as Pravy 30mg Tablet may cause weight loss.
Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pravy 30mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Is Pravy 30mg Tablet an immunosuppressant?
No, Pravy 30mg Tablet is not an immunosuppressant. It belongs to a class of medicines known as phosphodiesterase 4 inhibitors (PDE4) which work by blocking the activity of PDE4. PDE4 is found in inflammatory cells and blocking it helps in reducing the molecules responsible for inflammation.
Q. How long does it take for Pravy 30mg Tablet to work?
Pravy 30mg Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-term treatment and may take about 16 weeks to show an improvement.
Q. Can Pravy 30mg Tablet cause depression?
Yes, Pravy 30mg Tablet may cause depression as a side effect. The patient may also develop suicidal thoughts. It should be avoided in patients with a history of depression. In case you develop any of these symptoms, consult your doctor immediately or ask your friends or relatives to help seek medical advice.
Q. Does Pravy 30mg Tablet cause weight reduction?
Yes, Pravy 30mg Tablet may cause a decrease in appetite which may further cause weight loss. You should monitor your weight regularly while on treatment with Pravy 30mg Tablet. In case of significant weight loss, consult your doctor and consider stopping Pravy 30mg Tablet.