Premagan 10mg Tablet (10'S)

Manufacturer: Shine Pharmaceuticals Ltd

Salt Composition : Promethazine(10mg)


Premagan 10mg Tablet used in the treatment of nausea and vomiting related to certain conditions like before/after surgery or motion sickness. It may also be used to treat allergic conditions such as rash, itching, and runny nose.


Premagan 10mg Tablet should be taken with or without food, but take it at the same time every day to get the most benefit. The dose and how often you take it depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms.  You should take this medicine for as long as it is prescribed for you. If you miss a dose, take it as soon as you remember it. However, you should never take a double dose. Inform your doctor if your symptoms do not improve within 7 days of treatment.


The most common side effects of this medicine include dry mouth, blur vision, headache, and feeling dizzy. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes skin more sensitive to sunlight. Use a sunscreen or wear protective clothing before going out.


Before taking this medicine, let your doctor know if you have glaucoma or have asthma issues, or have high blood pressure. Inform your doctor if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment.



Basic Information

Mechanism Of Action

Promethazine is a an antagonist of histamine H1, post-synaptic mesolimbic dopamine, alpha adrenergic, muscarinic, and NMDA receptors. The antihistamine action is used to treat allergic reactions. Antagonism of muscarinic and NMDA receptors contribute to its use as a sleep aid, as well as for anxiety and tension.

Pharmacokinets

Promethazine hydrochloride is well absorbed from the gastrointestinal tract, although a significant portion of a dose is subject to first-pass metabolism. Clinical effects are apparent within 20 minutes after oral, rectal, or intramuscular administration, and the effects last four to six hours.

Side Effects

Unusual production of breast milk in women and men


Contra Indications

decreased function of bone marrow.

a type of movement disorder called parkinsonism.

neuroleptic malignant syndrome, a reaction characterized by fever, muscle rigidity and confusion.

a low seizure threshold.

closed angle glaucoma.

decreased lung function.

stenosing peptic ulcer

Pregnancy Related Information

Premagan 10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Premagan 10mg Tablet may cause excessive drowsiness with alcohol.


Breast Feeding Related Information

Premagan 10mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

For prolonged use and repeated doses of Premagan 10mg Tablet, observe the baby for excessive sleepiness.


Indications

Promethazine tablets and suppositories are indicated to treat rhinitis, allergic conjunctivitis, allergic reactions to blood or plasma, dermographism, anaphylactic reactions, sedation, nausea, vomiting, pain, motion sickness, and allergic skin reactions.


Interactions

acute alcohol intoxication.

cardiovascular disease.

CNS depression.

head injury.

antidopaminergic effects 1.

asthma.

anticholinergic effects.

asthma/COPD.


Typical Dosage

Swallow it as a whole. Do not chew, crush or break it. Premagan 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Premagan 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Premagan 10mg Tablet helps treat nausea, vomiting and allergic conditions

Use caution while driving or doing anything that requires concentration as Premagan 10mg Tablet can cause dizziness and sleepiness.

Do not drink alcohol while taking this medication as it may cause increased sleepiness.

It may make your skin more sensitive to sunlight. Avoid exposing your skin to strong sunlight, use a sunscreen lotion or make sure your skin is protected with clothing.

Do not take it for longer than 7 days. If your symptoms worsen or do not improve after 7 days, talk to your doctor.

Stop taking it at least three days before taking an allergy test as it can affect the test results.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Premagan 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. Is Premagan 10mg Tablet or Premagan 10mg Tablet DM syrup a narcotic/opiate/pain killer?

Premagan 10mg Tablet is antihistaminic drug and not a narcotic/opiate/pain killer. Patient should follow the advice of doctor regarding its use

Q. Is Premagan 10mg Tablet over the counter?

No, it is available with doctor's prescription only

Q. Can I take Premagan 10mg Tablet for a hangover/sore throat/ nausea/stomach flu/cramps/toothache/ headache/ cough/pain?

Premagan 10mg Tablet is used for treatment of symptoms of allergies, but not used for hangover, sore throat, stomach flu, cramps, toothache, headache and cough. Patient should follow the advice of doctor regarding its use

Q. Can I take Premagan 10mg Tablet with Nyquil/ codeine and ibuprofen/ Tylenol/ oxycodone/ Benadryl/ Dayquil/ Zofran/codeine and Nyquil/Xanax?

Yes, but taking other medicines may alter the effects of Premagan 10mg Tablet. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required