Manufacturer: Vhb Life Sciences Inc
Salt Composition : Procarbazine(50mg)
Procarb 50mg Tablet can be taken with or without food, but better to take it at the same time every day to get the most benefits. Some food or drinks can affect the working of medicine, so better to avoid mature cheeses (including processed cheeses), yeast or meat extracts and some type of beer or alcohol. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Moreover, it can make you infertile, so ask your doctor about safety methods.
Procarbazine belongs to a group of medicines called antineoplastic alkylating agents. It works by inhibiting protein, RNA, and DNA synthesis, which helps to stop the growth of cancer cells in the body.
Procarbazine is a nonclassic alkylating agent. It is extensively metabolized to active alkylating species in a multistep oxidative process chiefly involving the cytochrome P450 enzyme complex but also monoamine oxidase and other cytosolic enzymes.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Procarb
Nausea
Vomiting
Decreased appetite
contraindicated in patients with known hypersensitivity to the drug or inadequate marrow reserve as demonstrated by bone marrow aspiration. Due consideration of this possible state should be given to each patient who has leukopenia, thrombocytopenia or anemia.
Procarb 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol while taking Procarb 50mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Procarb 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Procarbazine is indicated in the treatment of Hodgkin's lymphoma in children aged 2-18, when associated with other antineoplastic drugs in an appropriate protocol.
Drug-Drug Interactions: PROCARBAZINE may interact with painkillers (pethidine), ADHD medicines (atomoxetine, bupropion, buspirone), anti-migraine drugs (triptans), narcotics (methadone, tapentadol), certain supplements (such as tryptophan, tyramine), certain drugs for Parkinson's disease (entacapone, levodopa, tolcapone), diet-pills and food suppressants (diethylpropion), antipsychotic (clozapine), antihypertensives (ramipril, enalapril, losartan), antiepileptics (phenytoin, carbamazepine) and anti-depressants (fluoxetine, duloxetine, venlafaxine, St John’s wort).
Drug-Food Interactions: PROCARBAZINE can interact with alcohol and tobacco.
Drug-Disease Interactions: PROCARBAZINE should be used with caution in patients with a known hypersensitivity disorder, asthma, diabetes mellitus, epilepsy, stroke, heart failure, liver disease, kidney disease, blood disorder, clotting problems and non-cancerous tumours such as phaeochromocytoma.
Drug-Drug Interactions Checker List:
ATOMOXETINE
BUSPIRONE
SUMATRIPTAN
PETHIDINE
METHADONE
TAPENTADOL
TRYPTOPHAN
RAMIPRIL
ENALAPRIL
LOSARTAN
PHENYTOIN
CARBAMAZEPINE
CLOZAPINE
FLUOXETINE
DULOXETINE
ENTACAPONE
LEVODOPA
Do not chew, crush or break it. Procarb 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
Take it with or without food, but try to have it at the same time every day.
As a precaution, foods high in tyramine (eg. aged cheeses, air-dried meats, soy sauce, tap/draft beers and red wines) should be avoided when taking Procarb 50mg Tablet to avoid a serious reaction.
Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
It makes you feel dizzy. Do not drive or operate machinery until you know how it affects you.
Consult with your doctor if you are planning pregnancy as it can affect your fertility.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Procarb 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Avoid Procarb 50mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
