Manufacturer: Wockhardt Ltd
Salt Composition : Progesterone(200mg)
Proceive SR 200 Tablet is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken without food, preferably in the evening or at bedtime. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.
The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently. If you experience dizziness or tiredness, avoid driving or activity which requires mental concentration.
Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine.
Estrogen and progesterone are steroid hormones that play a pivotal role in the regulation of mammalian reproduction. One primary action of these hormones is to regulate the development and function of the uterus. These hormones act by regulating the transcription of specific genes in the uterus.
Progesterone is used by the sublingual route at dosages of 50 to 150 mg three to four times per day. A single 100 mg sublingual dose of Luteina has been found to reach mean peak progesterone levels of 13.5 ng/mL after 1 to 4 hours, with an elimination half-life of about 6 to 7 hours.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Proceive
Abdominal bloating
Hot flushes
Vaginal discharge
Urinary incontinence
Headache
Fatigue
Joint pain
Cough
Abnormal menstrual bleeding
Musculoskeletal (bone, muscle or joint) pain
Slurred speech
Pain behind eyes
Vertigo
Severe side effects of Proceive
Nausea
Sleepiness
Abdominal pain
Absence of menstrual periods
Itching
Change in body weight
Breast tenderness
Depression
Abnormal vaginal bleeding
Menstrual disorder
Edema (swelling)
Changes in cervical ectropion
Changes in cervical secretion
Cholestatic jaundice
Nipple discharge
Injection site reactions (pain, swelling, redness)
Red spots or bumps
Acne
Hair loss
Excessive hair growth on face
Anaphylactic reaction
Fever
Insomnia (difficulty in sleeping)
Progesterone is contraindicated in patients with pre-existing breast cancer or cancer of reproductive organs, such as cervical cancer, endometrial cancer, ovarian cancer, uterine cancer, or vaginal cancer. Likewise, progesterone formulations should not be used in patients with undiagnosed vaginal bleeding.
Proceive SR 200 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
It is not known whether it is safe to consume alcohol with Proceive SR 200 Tablet. Please consult your doctor.
Proceive SR 200 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Progestins, by themselves or in combination contraceptives, can be used to treat dysmenorrhea, irregular menstruation, abnormal uterine bleeding, and endometriosis-related pain. They are also indicated in the diagnostic evaluation of secondary amenorrhea.
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Do not chew, crush or break it. Proceive SR 200 Tablet is to be taken empty stomach.
Store below 30°C
Proceive SR 200 Tablet is used in the treatment of female infertility and as a part of hormone replacement therapy.
It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
It should be taken without food, preferably in the evening or at bedtime.
It may cause sleepiness or drowsiness. Don't drive or do anything that requires mental focus until you know how Proceive SR 200 Tablet affects you.
It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Proceive SR 200 Tablet is to be taken empty stomach.
Q. Can you take Proceive SR 200 Tablet every day?
Yes, Proceive SR 200 Tablet can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.
Q. Does Proceive SR 200 Tablet cause weight gain?
Yes, taking Proceive SR 200 Tablet may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Proceive SR 200 Tablet is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.
Q. How is progesterone beneficial for fertility and pregnancy?
Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. Proceive SR 200 Tablet (form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.