Ptu 50mg Tablet (100'S)


PTU Tablet may be used alone or in combination with other medicines. It can be taken with or without food. It should be taken exactly as prescribed by your doctor. Your doctor will decide the dose and how often you should take them. You should take this medicine regularly to get the most benefit from it. Do not stop taking the medicine even if you feel better unless the doctor tells you so.


Taking this medicine may cause some common side effects such as skin rash, hair loss, headache, pain (joint, nerve, or muscle pain), nausea, and paresthesia (tingling or pricking sensation). Let your doctor know if any of these side effects do not go away with time or get worse.


Before using this medicine, inform your doctor if you have any problems with your liver or kidneys. You should also tell your doctor all the other medications you are taking. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.


Basic Information

Mechanism Of Action

PTU Tablet is an anti-thyroid medication. It works by reducing the amount of thyroid hormones produced by the thyroid gland.

Pharmacokinets

Propylthiouracil is readily absorbed and is extensively metabolized. Approximately 35% of the drug is excreted in the urine, in intact and conjugated forms, within 24 hours.

Side Effects

Taking this medicine may cause some common side effects such as skin rash, hair loss, headache, pain (joint, nerve, or muscle pain), nausea, and paresthesia (tingling or pricking sensation).

Contra Indications

COntraindications include a previous history of hypersensitivity to PTU or any of its drug components. Caution is advised in patients with hepatic impairment or myelosuppression and pediatric patients.

Pregnancy Related Information

PTU Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with PTU Tablet. Please consult your doctor.

Breast Feeding Related Information

PTU Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Indications

Hyperthyroidism treatment.

Used if methimazole or radioactive iodine treatment is contraindicated or as an alternative treatment option in a patient with Graves disease or toxic multinodular goiter[1]

Used before thyroidectomy or radioactive iodine therapy to treat hyperthyroidism.

Interactions

Drug-Drug Interactions: PROPYLTHIOURACIL may interact with blood thinners (warfarin, coumadin), digitalis glycoside (digoxin), xanthines (theophylline, aminophylline), and mineral supplements containing iodine.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: PROPYLTHIOURACIL should be used with caution in patients with a known hypersensitivity disorder, HIV, liver disease, kidney disease or blood disorders such as agranulocytosis and thrombocytopenia.

Drug-Drug Interactions Checker List:

WARFARIN

COUMADIN

DIGOXIN

THEOPHYLLINE

AMINOPHYLLINE

IODINE

Typical Dosage

Do not chew, crush or break it. PTU Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

PTU Tablet is used for the treatment of hyperthyroidism.

You may have to stop taking it for a while if you are also taking radio-iodine as a treatment for your overactive thyroid.

It may affect the level of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness.

Stop taking PTU Tablet and Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.

Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. PTU Tablet may be taken with or without food, but it is better to take it at a fixed time.