Manufacturer: Dr Reddy's Laboratories Ltd
Salt Composition : Bendamustine(100mg)
Purplz 100mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, infection, fatigue, nausea, and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Purplz 100mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
Results of a human mass balance study confirm that bendamustine is extensively metabolized via hydrolytic, oxidative, and conjugative pathways. Mean recovery of total radioactivity in cancer patients following IV infusion of [14C] bendamustine hydrochloride was approximately 76% of the dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Purplz
Anemia (low number of red blood cells)
Decreased white blood cell count
Infection
Fatigue
Nausea
Fever
Vomiting
Low blood platelets
Mucosal inflammation
Contraindications include a known hypersensitivity to mannitol or bendamustine. Patients should be closely monitored for reactions or symptoms during the first cycle of therapy. Therapy should be discontinued if severe reactions occur.
Purplz 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Purplz 100mg Injection. Please consult your doctor.
Purplz 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Bendamustine Hydrochloride Injection is indicated for the treatment of patients with indolent B- cell non-Hodgkin lymphoma that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen.
Drug-Drug Interactions: BENDAMUSTINE may interact with vaccines, CYP1A2 inhibitors (ketoconazole, clopidogrel, ritonavir, imipramine, clozapine), CYP1A2 inducers (Cimetidine, rifampicin, verapamil, phenytoin), monoclonal antibodies ((etanercept, baricitinib, certolizumab, golimumab, infliximab), vaccines and other medicines.
Drug-Food Interactions: Avoid alcohol consumption and smoking.
Drug-Disease Interactions: Inform your doctor if you have kidney or liver disease, skin diseases, and infections before receiving BENDAMUSTINE.
Drug-Drug Interactions Checker List:
KETOCONAZOLE
CLOPIDOGREL
RITONAVIR
CLOZAPINE
CIMETIDINE
RIFAMPICIN
PHENYTOIN
ETANERCEPT
GOLIMUMAB
INFLIXIMAB
BARICITINIB
Store below 30°C
If you miss a dose of Purplz 100mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Purplz 100mg Injection is given as an injection into vein under the supervision of a doctor.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Purplz 100mg Injection safe?
Purplz 100mg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. How does Purplz 100mg Injection work?
Purplz 100mg Injection works by destroying the DNA, thus killing the existing cancer cells and also preventing the growth and spread of new cancer cells.
Q. Is Purplz 100mg Injection a vesicant?
Purplz 100mg Injection has vesicant properties and can seriously damage skin and underlying fat if leaks during administration.
Q. Does Purplz 100mg Injection cause hair loss/constipation?
Yes, hair loss and constipation are the common side effects of Purplz 100mg Injection.
