Manufacturer: Merck Ltd
Salt Composition : Quinine(300mg)
Vial of 2ml Injection
(Inclusive of all taxes)
Quinine Dihydrochloride 300mg Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. Take measures to reduce the chance of being bitten by mosquitoes like using insect repellent creams on parts of your body, not covered by clothing. Spray mosquito repellent to kill any mosquitoes that may have entered rooms despite screening. Wear light-colored and covered clothing when you are outside after sunset.
Some people may experience vomiting, deafness, headache, and dizziness as side effects of this medicine. You may also notice some injection site reactions like pain, swelling, or redness. Please consult your doctor if these side effects do not resolve or persist for a longer duration.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. It may cause blurring of vision. Therefore, regular eye examinations are recommended while on treatment with this medicine. When used long-term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly. Inform your doctor if you have unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.
Mechanism of Action: Quinine inhibits nucleic acid synthesis, protein synthesis, and glycolysis in Plasmodium falciparum and can bind with hemazoin in parasitized erythrocytes. However, the precise mechanism of the antimalarial activity of quinine sulfate is not completely understood.
Also, the pharmacokinetics (PK) of quinine are known to vary as patients recover from malaria, with an expansion of the volume of distribution and an increase in systemic clearance resulting in a decline of the average concentration of quinine in plasma
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Quinine Dihydrochloride
Vomiting
Deafness
Headache
Dizziness
Injection site reactions (pain, swelling, redness)
a significant complication of malaria called blackwater fever.
low blood sugar.
low amount of potassium in the blood.
hemolytic uremic syndrome, a condition that affects the kidney and the blood.
decreased blood platelets.
myasthenia gravis, a skeletal muscle disorder.
Quinine Dihydrochloride 300mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Quinine Dihydrochloride 300mg Injection. Please consult your doctor.
Quinine Dihydrochloride 300mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Quinine is used alone or with other medications to treat malaria (a serious or life-threatening illness that is spread by mosquitos in certain parts of the world). Quinine should not be used to prevent malaria. Quinine is in a class of medications called antimalarials.
Quinine has no known severe interactions with other drugs.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Quinine Dihydrochloride 300mg Injection, consult your doctor.
Consult a doctor before taking any medicines.
Quinine Dihydrochloride 300mg Injection helps in the treatment of malaria.
Do not drive or do anything that requires mental focus until you know how Quinine Dihydrochloride 300mg Injection affects you.
Have regular eye tests done while you are taking this medicine. Stop taking Quinine Dihydrochloride 300mg Injection and immediately inform your doctor if you notice any changes in your vision.
Inform your doctor if you develop a rash or ringing in your ears.
It can cause lowering of blood sugar level. Inform your doctor if you experience symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Who should not use Quinine Dihydrochloride 300mg Injection?
Use of Quinine Dihydrochloride 300mg Injection should be avoided in patients who are allergic to Quinine Dihydrochloride 300mg Injection or any of its components. However, if you are not aware of any allergy or if you are using Quinine Dihydrochloride 300mg Injection for the first time, consult your doctor.
Q. What should I tell my doctor before starting treatment with Quinine Dihydrochloride 300mg Injection?
Before starting treatment with Quinine Dihydrochloride 300mg Injection, inform your doctor if you have any other health conditions like kidney or heart-related problems. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Also, let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant or breastfeeding.
Q. Is Quinine Dihydrochloride 300mg Injection safe?
Quinine Dihydrochloride 300mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. How long does it take for malaria symptoms to show?
Symptoms of malaria can develop as quickly as 7 days after you are being bitten by an infected mosquito. Typically, the time between being infected and the appearance of symptoms (incubation period) is 7 to 18 days. However, in some cases it can take up to one year for the symptoms to develop. Initial symptoms of malaria are flu-like which include feeling hot and shivery, muscle pains, vomiting, headaches and diarrhea.
