Manufacturer: Bayer Pharmaceuticals Pvt Ltd
Salt Composition : Regorafenib(40mg)
Resihance 40Mg Tablet is a drug targeted basically on cancerous diseases. The main method of its function is blocking cancer cells proteins which encourages growth of such cells, hence its also known as cancer growth blocker. FDA in 2017 has expanded the indications of Resihance 40Mg Tablet to include hepatocellular carcinoma. It has been also included as a potential cure agent for multiple types of tumor. It is administered to treat and delay tumor growth in patients with gastrointestinal stromal tumors. It is indicated for treating colorectal cancer as well.
Resihance 40Mg Tablet comes usually in tablet format which is taken once a day according to the doctor’s advice. It is ideally taken in the same time every day. It has been seen that it is usually prescribed to be taken every day for 3 weeks then 1 week gap is given before restarting the dosage.
Side effects are very alarming in some cases when taken without professional guidance. Severe liver toxicity, bleeding, skin-peeling, blood pressure are some of the serious effects. Weakness, fatigue, loss of appetite, diarrhea, weight loss, infections etc are some common side effects which accompany the drug. Hence it must be taken only under Doctor’s advice.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.
The active constituent of this medicine is a tiny molecule inhibitor of manifold membrane-bound and intracellular kinases associated with normal cellular functions and in pathologic procedures like oncogenesis, tumour angiogenesis, and the retention of the tumour microenvironment.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.
Regorafenib undergoes enterohepatic circulation with multiple plasma concentration peaks observed across the 24-hour dosing interval. Regorafenib is highly bound (99.5%) to human plasma proteins. Regorafenib is metabolized by CYP3A4 and UGT1A9.
Rash
Weakness
Reduced Blood Platelets
Difficulty In Speaking
Haemorrhage
Vomiting
Pain
Nausea
Infections
Hair Loss
Fever
Anemia
Diarrhoea
Increased Blood Pressure
Decreased Appetite
Mucosal Inflammation
Stomatitis (Inflammation Of The Mouth)
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.
This medicine may cause serious skin problems, including hand-foot skin reaction or a severe rash. Call your doctor right away if you have skin redness, pain, blisters, bleeding, or swelling of the palms of your hands and soles of your feet. This medicine may cause serious heart problems.
Resihance 40mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Interaction with alcohol is unknown. Please consult your doctor.
Resihance 40mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
indicated for the treatment of patients with metastatic colorectal cancer (CRC) who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if RAS wild- type, an anti-EGFR therapy.
Drug-Drug Interactions: REGORAFENIB may have interaction with strong CYP3A4 inhibitors (clarithromycin, diltiazem, erythromycin, itraconazole, ketoconazole, ritonavir), strong CYP3A4 inducers (carbamazepine, rifampicin, phenytoin, phenobarbitone).
Drug-Food Interactions: Avoid alcohol consumption and smoking.
Dug-Disease Interactions: Tell your doctor if you have liver or kidney disease, heart problems, GI perforation, or lung toxicity before starting the treatment.
Drug-Drug Interactions Checker List:
CLARITHROMYCIN
RITONAVIR
KETOCONAZOLE
ITRACONAZOLE
RIFAMPICIN
PHENYTOIN
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.
