Respin 1mg Tablet MD (10'S)

Mechanism Of Action

RESPIN MD 1MG TABLET shows antipsychotic activity by blocking certain receptors (D2 and 5-HT2) in the brain, thus decreasing symptoms of schizophrenia and mood disorders.

Pharmacokinets

The relative oral bioavailability of risperidone from a tablet is 94% (CV=10%) when compared to a solution. The volume of distribution of risperidone is approximately 1 to 2 L/kg. Risperidone and its active metabolite, 9-hydroxyrisperidone, are ~88% and ~77% protein-bound in human plasma, respectively.

Side Effects

COMMON

Difficulty falling or staying asleep, feeling sleepy, impaired alertness

Parkinsonism (slow or impaired movement, sensation of stiffness or tightness of the muscles, sensation of freezing up and then restarting, slow shuffling walk, increased saliva or drooling, a loss of expression on the face, a tremor while at rest)

Headache

Dizziness

Tremor

Raised levels of a hormone called "prolactin" (symptoms in men include breast swelling, difficulty in getting or maintaining erections, decreased sexual desire or other sexual dysfunction. In women they may include leakage of milk from the breasts, breast discomfort, missed menstrual periods, or other problems with your cycle or fertility problems)

Pneumonia (infection of the lungs), common cold and flu symptoms, sinus infection

Urinary tract infection

Ear infection

Weight gain, raised appetite, weight loss, decreased appetite

Irritability, depression, anxiety (worry, uneasiness), restlessness, sleep disturbances

Dystonia (slow or sustained involuntary contraction of facial and other muscles including abnormal movements of the eyes, mouth, tongue or jaw)

Dyskinesia (involuntary muscle movements like repetitive, spasm-like movements, or twitching), tremor (shaking)

Blurred vision, infection of the eye (pink eye)

Fast heart rate, raised blood pressure, shortness of breath

Throat pain, cough, nose bleeds, stuffy nose

Stomach pain and discomfort, vomiting, nausea, constipation, diarrhoea, indigestion, dry mouth

Toothache

Rash, skin redness

Muscle spasms, or bone, muscle, back and joint pain

Incontinence (lack of control) of urine

Swelling of the body, arms or legs

Chest pain, weakness, fatigue (tiredness), pain

Fall

UNCOMMON

Infection of the eye, tonsils, nails, skin, an infection confined to a single area of skin or part of the body, viral infection, skin inflammation due to mites

Diabetes (high blood sugar), too much drinking of water

Increased blood cholesterol

Mania (excited mood), confusion, reduced sexual drive, nervousness, nightmares

Unresponsive to stimuli, loss or low level of consciousness

A restless urge to move parts of your body, balance disorder, abnormal coordination, dizziness upon standing, disturbance in attention, speech problems, loss or abnormal sense of taste, reduced sensation of skin to pain and touch, a tingling, pricking sensation or numbness of skin

Increased sensitivity of the eyes to light, dry and red eyes, increased tears

Vertigo (spinning sensation), ringing in the ears, ear pain

Palpitations (fluttering or pounding feeling in your chest)

Low blood pressure (especially while standing up), flushing

Stomach or intestinal infection, lack of voluntary control over defecation, very hard stool, difficulty swallowing, excessive passing of gas or wind

Itching, hair loss, thickening of skin, eczema (an inflammatory skin condition), dry and discolored skin, acne, flaky, itchy scalp, skin disorder, skin lesion

Abnormal posture, joint stiffness and swelling, weak muscles, neck pain

Frequent urination, inability to pass urine, pain when passing urine

Erectile dysfunction, ejaculation disorder

Loss of, or missed menstrual periods, or other problems with your cycle (females)

Development of breasts in men

Leakage of milk from the breasts, sexual dysfunction, breast pain and discomfort, vaginal discharge

Swelling of the face, eyes, lips or mouth

Chills, increase in body temperature

Change in the way you walk

Convulsions

Feeling unwell, chest discomfort

Pain related to diagnostic or treatment procedures

RARE

Infection

Sleep walking, sleep-related eating disorder

Inappropriate secretion of antidiuretic hormone (hormone controlling urine)

Sugar in the urine, raised blood triglycerides (type of fat)

Low blood sugar

Absence of emotion, inability to reach orgasm

Catatonia (unable to move or respond while awake)

Blood vessel problems in the brain

Coma due to uncontrolled diabetes

Shaking of the head

Glaucoma (increased pressure within the eyeball), eye rolling, problems with movement of your eyes, eyelid margin crusting

Eye problems during cataract surgery

Dangerously excessive intake of water

Chapped lips, swollen tongue, skin rash related to drug

Dandruff

Pain in muscles and breakdown of muscle fibres (rhabdomyolysis)

Irregular heartbeat

Trouble breathing during sleep, fast, shallow breathing

Inflammation of the pancreas

Raised blood insulin levels (a hormone that controls blood sugar levels)

Low body temperature, coldness in arms and legs

Symptoms of drug withdrawal

Jaundice (skin and the eyes appears yellowish)

Stop taking RESPIN MD 1MG TABLET and consult your doctor immediately if you experience any of the following side effects:

Have dementia and feel a sudden change in your mental state or sudden numbness or weakness involving your face, arms or legs, especially on one side, or slurred speech (even for a short period of time)

Experience tardive dyskinesia (uncontrollable twitching or jerking movements in your face, tongue, or other parts of your body)

Experience blood clots in the veins, particularly in the legs (symptoms include swelling, pain, and redness), which can travel through blood vessels to the lungs leading to chest pain and breathlessness

Experience severe allergic reaction indicated by fever, swelling of mouth, face, lip or tongue, breathlessness, itching, skin rash or low blood pressure

Glaucoma (increased pressure within the eyeball)

Rhabdomyolysis (breakdown of muscle fibres making the muscles weak and sores)

Extremely low numbers of the white blood cells needed to fight infection in your blood

High temperature, muscle stiffness, sweating or a lowered level of consciousness (Neuroleptic Malignant Syndrome)

If you are a man and experience prolonged or painful erection (priapism)

Contra Indications

contraindicated in patients with a known hypersensitivity to the product. Elderly patients with dementia treated with atypical antipsychotic drugs have an increased mortality compared to placebo in a meta-analysis of 17 controlled trials of atypical antipsychotic drugs,

Pregnancy Related Information

RESPIN MD 1MG TABLET is not recommended for use in pregnant women unless considered clearly necessary. If RESPIN MD 1MG TABLET is given in the last trimester of pregnancy it can cause agitation, hypertonia, hypotonia, tremor, sleepiness, respiratory distress, or feeding disorder in the newborn babies. Consult your doctor before taking RESPIN MD 1MG TABLET.

Product And Alcohol Interaction

Avoid consumption of alcohol while taking RESPIN MD 1MG TABLET as it may cause sedation.

Breast Feeding Related Information

RESPIN MD 1MG TABLET should be used with caution in breast-feeding women as it passes through breast milk. Consult your doctor before taking RESPIN MD 1MG TABLET.

Indications

Schizophrenia (in adults and children aged 13 and up)

Bipolar I acute manic or mixed episodes as monotherapy (in adults and children aged ten and up)

Bipolar I acute manic or mixed episodes adjunctive with lithium or valproate (in adults)

Autism-associated irritability (in children aged five and up)

Interactions

Before taking RESPIN MD 1MG TABLET, inform your doctor if you are taking any of the following medicine:

Benzodiazepines (used to calm you down) Ex. diazepam, lorazepam

Opiates (used to reduce pain) Ex. morphine, codeine

Antihistamines (used in allergies) Ex. brompheniramine, chlorpheniramine

Medicines used for heart conditions (to treat irregular heart rhythms, high blood pressure) Ex. quinidine, furosemide, chlorthiazide, verapamil

Antidepressants (used to treat depression) Ex. fluoxetine, paroxetine

Medicines that cause a slow heartbeat (Ex. Diltiazem, atenolol)

Anti-parkinsonian drugs (used to treat parkinsonism) Ex. Levodopa

Psychostimulants (used to treat attention deficit hyperactivity disorder (ADHD)) Ex. Methylphenidate

Rifampicin (used to treat infections)

Anti-epileptics (used to treat fits) Ex. carbamazepine, phenytoin, phenobarbital

Phenothiazines (used to treat psychosis or to calm down) Ex. Chlorpromazine, fluphenazine

H2 blockers (used to treat peptic ulcers) Ex. cimetidine, ranitidine

Anti-fungals (used to treat fungal infections) Ex. itraconazole, ketoconazole

Anti-retrovirals (used to treat HIV/AIDS) Ex. ritonavir

Sertraline, fluvoxamine (used to treat depression and other psychiatric disorders)

Typical Dosage

Swallow RESPIN MD 1MG TABLET with a glass of water. Do not crush or chew the medicine.

Storage Requirements

Keep RESPIN MD 1MG TABLET out of reach of children

Do not store RESPIN MD 1MG TABLET above 25°C

Effects Of Overdose

If you or anyone else accidentally take too much of RESPIN MD 1MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of RESPIN MD 1MG TABLET overdose are feeling sleepy or tired, or having abnormal body movements, problems standing and walking, feeling dizzy due to low blood pressure, or having abnormal heartbeats or fits.

Expert Advice

Know any factors that would cause stroke like high blood pressure or blood vessel issues in the brain

Have ever had involuntary movements of the tongue, mouth and face

Have ever had a condition having symptoms like high temperature, muscle stiffness, sweating or a lowered level of consciousness (also known as Neuroleptic Malignant Syndrome)

Have Parkinson’s disease (shaking, stiffness, and difficulty with walking, balance, and coordination) or dementia (memory loss)

Are diabetic (having low blood sugar levels)

Have epilepsy (fits)

Are a man and you have ever experienced a prolonged or painful erection

Find it difficult controlling your body temperature or overheating

Have a tumour

Or any member of your family has a history of blood clots

Are about to have any eye operation

How To Use

Take RESPIN MD 1MG TABLET as advised by your physician. This medicine can be taken with or without meals.

For Tablet, Capsule: Swallow RESPIN MD 1MG TABLET with a glass of water. Do not crush or chew the medicine.

For Mouth Dissolving Tablet, Orally Disintegrating Tablet: Place RESPIN MD 1MG TABLET inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of disease condition. Continue to take RESPIN MD 1MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.

FAQs

Can RESPIN MD 1MG TABLET cause seizures?

Yes. Seizures are one of the serious side effects of RESPIN MD 1MG TABLET. Immediately consult your doctor if you feel any symptoms such as uncontrollable jerking movements of hands and legs, loss of consciousness, fear, anxiety or temporary confusion after taking RESPIN MD 1MG TABLET.

Can RESPIN MD 1MG TABLET be used for sleep?

Some studies have suggested that RESPIN MD 1MG TABLET can improve the quality of sleep in schizophrenic patients. Consult your doctor before taking RESPIN MD 1MG TABLET for sleep.

Can RESPIN MD 1MG TABLET cause weight gain?

Yes. Weight gain is one of the common side effects of RESPIN MD 1MG TABLET. Consult your doctor if you feel like you are gaining weight or there is an increase in your appetite after taking RESPIN MD 1MG TABLET.

Can RESPIN MD 1MG TABLET be used for anxiety?

It has been found that low dose of RESPIN MD 1MG TABLET as adjuvants to SSRIs (Selective serotonin reuptake inhibitors) are useful in generalized anxiety disorder. Consult your doctor before taking RESPIN MD 1MG TABLET for anxiety.