Manufacturer: Cipla Ltd
Salt Composition : Reteplase(18mg)
Retefast 18mg Injection is an injectable drug, given directly into a vein and it is given by a doctor as soon as possible after the first signs of a heart attack. Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely. You may be given another medicine to stop blood clotting at the same time or after the treatment.
This medicine may increase your risk of bleeding, so it is better to be careful while shaving, cutting nails, or using sharp objects. Treatment with this drug can also cause nausea, vomiting, decreased blood pressure, and injection site bleeding.
This drug needs to be administered with care by an expert and is not suitable for everyone. There is a long list of situations where you will not be given Retefast 18mg Injection including if you have had a head injury or surgery on your brain or spinal cord and any current bleeding anywhere in your body. Your healthcare team will need to know a lot about your medical history before giving you this medicine.
Retefast 18mg Injection is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.
(reteplase) is a recombinant plasminogen activator which catalyzes the cleavage of endogenous plasminogen to generate plasmin. Plasmin degrades the fibrin matrix of the thrombus, exerting its thrombolytic action.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Retefast
Bleeding disorder
Nausea
Vomiting
Decreased blood pressure
Injection site bleeding
Active internal bleeding.
Recent stroke.
Intracranial or intraspinal surgery or serious head trauma within 3 months.
Retefast 18mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Retefast 18mg Injection. Please consult your doctor.
Retefast 18mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Reteplase is a purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells.
Drug-Drug Interactions: Inform your doctor if you are taking anti-coagulants (heparin, enoxaparin, warfarin, phenindione, aspirin, dipyridamole, ticlopidine, clopidogrel, vitamin K antagonists).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have/had cancer, stroke, high blood pressure, active ulcer in the stomach or intestine, portal hypertension, inflammation of the pancreas, bleeding behind or in the eye, or severe liver or kidney problems.
Drug-Drug Interactions Checker List:
HEPARIN
ENOXAPARIN
WARFARIN
PHENINDIONE
ASPIRIN
DIPYRIDAMOLE
TICLOPIDINE
CLOPIDOGREL
Kindly do not self administer.
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
It should be given as soon as possible (within 12 hours) after the onset of a heart attack or within 4.5 hours of onset of stroke.
Let your doctor know immediately if you develop any nosebleeds, gum bleeding, black or tarry stools, or bruising.
Do not discontinue the medicines started after this injection as it may increase your chances of having another heart attack or stroke.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How is Retefast 18mg Injection administered?
Retefast 18mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Retefast 18mg Injection.
Q. Is Retefast 18mg Injection safe?
Retefast 18mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. Can the use of Retefast 18mg Injection increase the risk of bleeding?
Yes, Retefast 18mg Injection can increase the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Q. What medicines should I avoid while taking Retefast 18mg Injection?
Retefast 18mg Injection can interact with several medicines. If you are already taking Retefast 18mg Injection, do not take any other medicine without talking to your doctor.
