Manufacturer: Johnson & Johnson Ltd
Salt Composition : Anti Rh D Immunoglobulin(50mcg)
Rhogam 50mcg Injection is given for Rh prophylaxis in pregnancy-related complications. It is also approved for Incompatible transfusions in Rh-negative individuals transfused with blood components containing Rh-positive red blood cells (RBCs). It may also be used for immune thrombocytopenic purpura, a condition wherein the number of circulating platelets decrease leading to easy bruising.
Your doctor or nurse will give you this injection. Kindly do not self administer. The injection is given into a muscle; normally it is given in the upper arm. You will be offered an anti-D injection routinely at 28 weeks of pregnancy and within 72 hours of birth if your baby is Rh D positive.
This medicine may sometimes cause side effects like fever, headache, feeling of discomfort, and injection site tenderness or pain. If you get any of these, or other reactions, or just feel unwell, you should tell your doctor. There may be ways of preventing or reducing these effects.
Before using it, you should tell your doctor if you have any problems with blood clotting and if you have recently had, or plan to have, a vaccination.
Anti-Rh D immunoglobulin belongs to class of drugs called immunoglobulin. It removes or nullifies any fetal rhesus-D positive red blood cells that enter the rhesus-D negative maternal blood stream during childbirth, abortion, or any accident or intervention during pregnancy which might lead to bleeding across the placenta.
Rh immune globulin (RhIG) is a medication that contains antibodies to Rh antigen D (RhD), which may be present on the surface of red blood cells (RBCs) in some individuals. It prevents a person's immune system from recognizing RhD, thus suppressing a potentially fatal immune reaction.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rhogam
Fever
Headache
Injection site tenderness
Injection site pain
Feeling of discomfort
A hemolytic reaction may result if given to Rh-positive patients; RhIG should be avoided in these individuals.
Patients with a history of severe hypersensitivity or anaphylaxis to any human immune globulin product.
Rhogam 50mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Rhogam 50mcg Injection. Please consult your doctor.
Rhogam 50mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Invasive prenatal diagnosis - eg, amniocentesis, chorionic villus biopsy.
Antepartum haemorrhage.
External cephalic version of the fetus (including attempted).
Ectopic pregnancy.
Evacuation of molar pregnancy.
Intrauterine death and stillbirth.
ANTI RH D IMMUNOGLOBULIN may interact with vaccine taken against measles, mumps, and rubella (MMR vaccine) and the vaccine has taken against chickenpox (varicella vaccine) and make them less effective.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Rhogam 50mcg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What does anti-D antibody mean?
If you're RhD negative, your blood will be checked for the antibodies (known as anti-D antibodies) that destroy RhD positive red blood cells. If anti-D antibodies are detected in your blood during pregnancy, there's a risk that your unborn baby may get affected by rhesus disease.
Q. Why do I need Rhogam 50mcg Injection?
Rhogam 50mcg Injection is needed to prevent a disease called Rhesus disease. This can help to avoid a process known as sensitisation in women. This is a condition when a woman with RhD negative blood is exposed to RhD positive blood and develops an immune response to it.
Q. How is Rhogam 50mcg Injection administered?
Rhogam 50mcg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. Rhogam 50mcg Injection is given into a muscle, normally in the upper arm. Follow your doctor’s instructions carefully to get maximum benefit from Rhogam 50mcg Injection.
Q. When is Rhogam 50mcg Injection given?
Rhogam 50mcg Injection will be given as an injection at 28 weeks of pregnancy and within 72 hours of birth, if your baby is Rh D positive. Consult your doctor before getting Rhogam 50mcg Injection.
