Rhogam UF 300mcg Injection (1ml)


Rhogam UF 300mcg Injection is given for Rh prophylaxis in pregnancy-related complications. It is also approved for Incompatible transfusions in Rh-negative individuals transfused with blood components containing Rh-positive red blood cells (RBCs). It may also be used for immune thrombocytopenic purpura, a condition wherein the number of circulating platelets decrease leading to easy bruising.



Basic Information

Mechanism Of Action

Anti-Rh D immunoglobulin belongs to class of drugs called immunoglobulin. It removes or nullifies any fetal rhesus-D positive red blood cells that enter the rhesus-D negative maternal blood stream during childbirth, abortion, or any accident or intervention during pregnancy which might lead to bleeding across the placenta.


Pharmacokinets

Rh immune globulin (RhIG) is a medication that contains antibodies to Rh antigen D (RhD), which may be present on the surface of red blood cells (RBCs) in some individuals. It prevents a person's immune system from recognizing RhD, thus suppressing a potentially fatal immune reaction.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rhogam UF

Fever

Headache

Injection site tenderness

Injection site pain

Feeling of discomfort

Contra Indications

A hemolytic reaction may result if given to Rh-positive patients; RhIG should be avoided in these individuals.

Patients with a history of severe hypersensitivity or anaphylaxis to any human immune globulin product.

Pregnancy Related Information

Rhogam UF 300mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Rhogam UF 300mcg Injection. Please consult your doctor.


Breast Feeding Related Information

Rhogam UF 300mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Invasive prenatal diagnosis - eg, amniocentesis, chorionic villus biopsy.

Antepartum haemorrhage.

External cephalic version of the fetus (including attempted).

Ectopic pregnancy.

Evacuation of molar pregnancy.

Intrauterine death and stillbirth.

Interactions

ANTI RH D IMMUNOGLOBULIN may interact with vaccine taken against measles, mumps, and rubella (MMR vaccine) and the vaccine has taken against chickenpox (varicella vaccine) and make them less effective.

Typical Dosage

 Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

For informational purposes only. Consult a doctor before taking any medicines.


Expert Advice

Your doctor or nurse will give you this medicine. Kindly do not self administer.


How To Use

Q. What does anti-D antibody mean?

If you're RhD negative, your blood will be checked for the antibodies (known as anti-D antibodies) that destroy RhD positive red blood cells. If anti-D antibodies are detected in your blood during pregnancy, there's a risk that your unborn baby may get affected by rhesus disease.

Q. Why do I need Rhogam UF 300mcg Injection?

Rhogam UF 300mcg Injection is needed to prevent a disease called Rhesus disease. This can help to avoid a process known as sensitisation in women. This is a condition when a woman with RhD negative blood is exposed to RhD positive blood and develops an immune response to it.

Q. How is Rhogam UF 300mcg Injection administered?

Rhogam UF 300mcg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. Rhogam UF 300mcg Injection is given into a muscle, normally in the upper arm. Follow your doctor’s instructions carefully to get maximum benefit from Rhogam UF 300mcg Injection.

Q. When is Rhogam UF 300mcg Injection given?

Rhogam UF 300mcg Injection will be given as an injection at 28 weeks of pregnancy and within 72 hours of birth, if your baby is Rh D positive. Consult your doctor before getting Rhogam UF 300mcg Injection.

FAQs

Q. What does anti-D antibody mean?

If you're RhD negative, your blood will be checked for the antibodies (known as anti-D antibodies) that destroy RhD positive red blood cells. If anti-D antibodies are detected in your blood during pregnancy, there's a risk that your unborn baby may get affected by rhesus disease.

Q. Why do I need Rhogam UF 300mcg Injection?

Rhogam UF 300mcg Injection is needed to prevent a disease called Rhesus disease. This can help to avoid a process known as sensitisation in women. This is a condition when a woman with RhD negative blood is exposed to RhD positive blood and develops an immune response to it.

Q. How is Rhogam UF 300mcg Injection administered?

Rhogam UF 300mcg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. Rhogam UF 300mcg Injection is given into a muscle, normally in the upper arm. Follow your doctor’s instructions carefully to get maximum benefit from Rhogam UF 300mcg Injection.

Q. When is Rhogam UF 300mcg Injection given?

Rhogam UF 300mcg Injection will be given as an injection at 28 weeks of pregnancy and within 72 hours of birth, if your baby is Rh D positive. Consult your doctor before getting Rhogam UF 300mcg Injection.