Riax 5mg Tablet (14'S)

Manufacturer: Dr Reddy's Laboratories Ltd

Salt Composition : Saxagliptin(5mg)


Riax 5mg Tablet is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or in combination with other diabetes medicines. It can be taken with or without food.


The dose will depend on your condition and blood sugar levels. Use it strictly as advised by your doctor. Do not stop taking the medicine unless your doctor recommends it. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.


The most common side effects of this medicine include hypoglycemia, upper respiratory tract infection, urinary tract infection, headache, and peripheral edema. It is important to recognize the symptoms of hypoglycemia (such as lightheadedness, sweating, dizziness, fainting, and dry mouth) and know how to deal with it. You can carry sugar or glucose candy and have them to control your symptoms if you experience any. Contact your doctor if any of these side effects do not go away or worry you.


Before taking this medicine, let your doctor know if you have ever had kidney disease, heart disease, or pancreas problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with this medicine's working. So, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.


Basic Information

Mechanism Of Action

Riax 5mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

Pharmacokinets

The metabolism of saxagliptin is primarily mediated by cytochrome P450 3A4/5 (CYP3A4/5). 50% of the absorbed dose will undergo hepatic metabolism. The major metabolite of saxagliptin, 5-hydroxy saxagliptin, is also a DPP4 inhibitor, which is one-half as potent as saxagliptin.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Riax

Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

Upper respiratory tract infection

Urinary tract infection

Headache

Peripheral edema

Contra Indications

Type I diabetes mellitus.

Allergic reaction to Saxagliptin.

Any severe infection.

Diabetic coma.

Pregnancy Related Information

Riax 5mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Product And Alcohol Interaction

It is unsafe to consume alcohol with Riax 5mg Tablet.

Breast Feeding Related Information

Riax 5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Indications

Saxagliptin is used along with diet and exercise to lower blood sugar levels in patients with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Saxagliptin is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors.

Interactions

Drug-Drug Interaction: SAXAGLIPTIN interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-HIV drugs (dolutegravir), ethanol, saliva reducing drugs (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine). Other drug interactions can contribute to an increased low blood sugar including sex hormones (androgens), anti-oxidant (alpha-lipoic acid), painkillers (aspirin), anti TB drugs (prothionamide), growth hormones (pegvisomant), and other antidiabetic medicines.

Drug-Food Interaction: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with SAXAGLIPTIN.

Drug-Disease Interaction: SAXAGLIPTIN should be used with caution in patients with a history of pancreatitis/pancreatic disease and renal dysfunction.

Drug-Drug Interactions Checker List:

BUPROPION

CIPROFLOXACIN

CIMETIDINE

DIGOXIN

DOLUTEGRAVIR

TOPIRAMATE

RANOLAZINE

ASPIRIN

Typical Dosage

Do not chew, crush or break it. Riax 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Riax 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Riax 5mg Tablet should be taken at the same time every day since this helps you remember to take it.

Be careful while driving or operating machinery until you know how Riax 5mg Tablet affects you.

It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.

Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.

Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Riax 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

FAQs

Q. Does Riax 5mg Tablet cause any weight loss (reduction)?

No, Riax 5mg Tablet neither causes weight loss nor weight gain. It is weight neutral. However, weight gain can be seen when Riax 5mg Tablet is used with other antidiabetic medicines like thiazolidinediones, sulfonylureas or insulin.

Q. What is the benefit of using Riax 5mg Tablet with insulin?

Riax 5mg Tablet when taken with insulin can help in lowering the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels). Consult your doctor as a dose adjustment of the two may be needed.

Q. Are there any contraindications to the use of Riax 5mg Tablet?

Yes, the use of Riax 5mg Tablet is contraindicated in some conditions like a history of allergy to Riax 5mg Tablet, any ingredients of this drug or to any other drug of the same class. Riax 5mg Tablet should also be avoided in patients with a history of pancreatitis.

Q. Is it beneficial to use Riax 5mg Tablet with glipizide?

Yes, it is beneficial to take Riax 5mg Tablet and glipizide. Both are antidiabetic drugs, however, they work in different ways. When taken together, they can help in better controlling of blood sugar levels.