Manufacturer: Lupin Ltd
Salt Composition : Isoniazid(150mg), Pyrazinamide(100mg), Rifampicin(375mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Rinizide 150 mg/100 mg/375 mg Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.
Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Rinizide 150 mg/100 mg/375 mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection.
The pharmacokinetics of isoniazid in man are described. Pronounced interindividual variation in circulating isoniazid concentration and clearance which occur after dosing with the drug are associated with hereditary differences in the acetylalor status.Pyrazinamide is used in the treatment of tuberculosis (TB) because its sterilizing effect against tubercle bacilli allows the shortening of treatment. It is part of standard treatment for drug-susceptible and drug-resistant TB, and it is being considered as a companion drug in novel regimens.Approximately 80% of rifampicin is transported in blood bound to plasma proteins, mainly albumin. Rifampicin is well distributed, although to a different degree, in the various tissues of the human body. Probably in the hepatocyte, rifampicin undergoes a process of desacetylation.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rinizide
Nausea
Vomiting
Fever
Rash
Dark colored urine
Sweating
Increased sputum production
Salivation
Watery eyes
Peripheral neuropathy (tingling and numbness of feet and hand)
Increased liver enzymes
Jaundice
Increased uric acid level in blood
Gout
Hypersensitivity to Rinizide Tablet is a contraindication . Hypersensitivity to Rinizide Tablet is a contraindication . In addition, Rinizide Tablet should not be used if you have the following conditions:
porphyria
allergy
Breastfeeding
Acute gout or hyperuricemia
pregnant
Pregnancy
hypersensitivity
alcohol
Liver disease
severe liver disease
Rinizide 150 mg/100 mg/375 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consuming alcohol while taking Rinizide 150 mg/100 mg/375 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Rinizide 150 mg/100 mg/375 mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Isoniazid+Pyrazinamide+Rifampicin is used in the treatment of tuberculosis.Isoniazid prevents the TB bacteria from forming their own protective covering while Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by these bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Pyrazinamide , on the other hand works by slowing the growth of these bacteria.
If you use other drugs or over the counter products at the same time, the effects of Rinizide Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all medications, vitamins and herbal supplements you use, so that your doctor can help you prevent or manage drug interactions. Rinizide Tablet may interact with the following drugs and products:
Aprepitant
Citalopram
Clopidogrel
Enalapril
eplerenone
Halothane
Imatinib
Imidapril
Leflunomide
mipomersen
Do not chew, crush or break it. Rinizide 150 mg/100 mg/375 mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Rinizide 150 mg/100 mg/375 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Rinizide 150 mg/100 mg/375 mg Tablet should be taken on an empty stomach but at the same time every day.
Do not skip any doses and finish the full course of treatment even if you feel better.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Rinizide 150 mg/100 mg/375 mg Tablet affects you.
Avoid drinking alcohol while taking this medicine as this may increase the risk of side effects on the liver.
Avoid taking hormone-based birth control methods as Rinizide 150 mg/100 mg/375 mg Tablet may decrease their effectiveness.
Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rinizide 150 mg/100 mg/375 mg Tablet is to be taken empty stomach.
Avoid Rinizide 150 mg/100 mg/375 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
