Manufacturer: Koye Pharmaceuticals Pvt ltd
Salt Composition : Rosuvastatin(10mg), Clopidogrel(75mg)
Rosupack-CV Capsule should be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like low-fat diet, exercise and not smoking may help this medicine to work better.
Stomach pain, diarrhea, indigestion, constipation, and headache are some common side effects of this medicine. This medicine increases your risk of bleeding, so it is important to be careful while shaving, cutting nails, using sharp objects, or engaging in contact sports (e.g., football, wrestling). Let your doctor know if you notice yellowing of skin, muscle pain or dark urine. You may be asked for regular monitoring of liver function while taking this medicine.
Before taking this medicine, tell your doctor if you have liver or kidney disease or you are suffering from bleeding disorder. You must tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Thus, clopidogrel is effectively used to reduce secondary vascular events such as thromboembolism in patients with atherosclerosis. Consequently, the combination therapy of rosuvastatin and clopidogrel should be beneficial for more effective management of cardiovascular diseases
Rosuvastatin is metabolized mainly by CYP2C9 and not extensively metabolized; approximately 10% is recovered as metabolite N-desmethyl rosuvastatin. It is excreted in feces (90%) primarily and the elimination half-life is approximately 19 hours.
When clopidogrel is ingested, 85% of prodrug is absorbed by liver and converted to its carboxylic acid derivative by carboxylic esterase. This is known as CLPM (clopidogrel metabolite), which is a major inactive metabolic product circulating in the blood and helps to determine the pharmacokinetics of the prodrug.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rosupack-CV
Indigestion
Diarrhea
Stomach pain
Constipation
Weakness
Headache
Dizziness
Muscle pain
Increased glucose level in blood
Increased liver enzymes
Rosuvastatin is contraindicated for use during pregnancy. Because HMG-CoA reductase inhibitors decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol (e.g., cell membranes), rosuvastatin may cause fetal harm when administered to pregnant women.
General Information. ...
Bleeding, GI bleeding, intracranial bleeding, peptic ulcer disease, surgery, trauma. ...
Hepatic disease. ...
Renal disease, renal failure, renal impairment. ...
Poor metabolizers. ...
Epidural anesthesia, labor, obstetric delivery, pregnancy, spinal anesthesia. ...
Breast-feeding. ...
Geriatric.
Rosupack-CV Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is unsafe to consume alcohol with Rosupack-CV Capsule.
Rosupack-CV Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
ROSUVASTATIN+CLOPIDOGREL is a combination drug composed of a blood-thinning agent and cholesterol-lowering agent, primarily used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our body.
Drug-Disease Interactions: ROSUVASTATIN+CLOPIDOGREL should not be given to the patients with active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), muscle problems or musculoskeletal problems (myopathy, rhabdomyolysis), asthma, and purpura (blood leakage under the skin).
Rosupack-CV Capsule may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Rosupack-CV Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Rosupack-CV Capsule to lower your risk of heart attacks and stroke.
Take it with food to avoid an upset stomach.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Notify your doctor if you are more tired than usual, do not feel hungry, or if you have yellow eyes, skin.
Notify your doctor if you experience muscle pain or weakness, particularly if accompanied with fever.
Let your doctor know you are taking Rosupack-CV Capsule before undergoing any surgical procedure.
Let your doctor know if you are pregnant, planning to conceive or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Rosupack-CV Capsule may be taken with or without food, but it is better to take it at a fixed time.
Q. Can the use of Rosupack-CV Capsule increase the risk of bleeding?
Yes, Rosupack-CV Capsule increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Q. What medicines should I avoid while taking Rosupack-CV Capsule?
Rosupack-CV Capsule can interact with several medicines and can cause serious problems. Talk to your doctor and inform him about using Rosupack-CV Capsule before taking any prescription or non-prescription medicine.
Q. Can Rosupack-CV Capsule cause muscle pain?
Yes, Rosupack-CV Capsule can cause muscle pain by injuring muscles. Talk to your doctor as soon as possible if you experience muscle pain, weakness or muscle cramps. It can be a sign of any muscle injury caused due to Rosupack-CV Capsule.
Q. Will I need to stop Rosupack-CV Capsule before surgery or dental procedure?
Rosupack-CV Capsule may increase the risk of bleeding during a surgery or dental procedure. Therefore, you may be asked by your doctor to stop taking Rosupack-CV Capsule. You should not stop taking Rosupack-CV Capsule on your own.