Salbair I Neb 1.25mg / 500mcg Transpules 2.5ml


Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your COPD may get worse. This medicine should not be used to relieve sudden shortness of breath. If sudden shortness of breath occurs, use your rescue inhaler. To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.

The most common side effects are dryness in mouth, shortness of breath, cough, tremor, headache, palpitations, and muscle cramp. If you get there, don’t stop taking it but do talk to your doctor. You can prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.


Basic Information

Mechanism Of Action

Salbair I Neb 1.25 Transpules 2.5ml is a combination of two medicines: Levosalbutamol and Ipratropium. Levosalbutamol is a bronchodilator while Ipratropium is an anticholinergic. They work by relaxing the muscles in the airways and widen the airways. Together, they make breathing easier.


Pharmacokinets

Levosalbutamol elicits an equal or slightly larger response than an equivalent dose of the racemic mixture. This is probably due to competitive inhibition between the enantiomers at beta-adrenoceptors. Pharmacokinetic-pharmacodynamic relationships for levosalbutamol show relatively large interindividual variations.Ipratropium is metabolized in the gastrointestinal tract by the activity of the cytochrome P-450 isoenzymes. From the orally administered dose, about 90% of the dose is excreted unchanged. The absorbed portion is partially metabolized by ester hydrolysis to inactive metabolites, tropic acid and tropane.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Salbair I Neb

Dryness in mouth

Breathlessness

Cough

Tremors

Headache

Palpitations

Muscle cramp

Contra Indications

It is not recommended to use Levosalbutamol+Ipratropium along with other medicines, such as anticholinergic, beta-adrenergic agents, beta-blockers, diuretics, digoxin, MAO inhibitors or anti-depressants.

Pregnancy Related Information

Salbair I Neb 1.25 Transpules 2.5ml may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Salbair I Neb 1.25 Transpules 2.5ml may cause excessive drowsiness with alcohol.


Breast Feeding Related Information

Salbair I Neb 1.25 Transpules 2.5ml is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Levosalbutamol + Ipratropium is a combination of two medicines that makes breathing easier for patients with chronic obstructive pulmonary disease (COPD). This medicine is for inhalation only. The tablet should not be swallowed. It should be taken at the same time each day.

Interactions

IPRATROPIUM+LEVOSALBUTAMOL may interact with bronchodilators (e.g. salmeterol, albuterol, and formoterol), steroid medicines (e.g. budesonide, prednisone), water pills or diuretic medicines (e.g. furosemide), anti-sickness medicines (e.g. ondansetron), heart-related medicines (e.g. atropine).

Typical Dosage

Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Salbair I Neb 1.25 Transpules 2.5ml, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Salbair I Neb 1.25 Transpules 2.5ml is a combination of two medicines that makes breathing easier for patients with chronic obstructive pulmonary disease (COPD).

This medicine is for inhalation only. The tablet should not be swallowed.

It should be taken at the same time each day.

It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.

Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.

Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.

Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.

Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Salbair I Neb 1.25 Transpules 2.5ml can lower blood potassium level.

Only miniscule amounts of Salbair I Neb 1.25 Transpules 2.5ml may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

How To Use

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.


FAQs

Q. Are there any medicines which I should avoid while taking Salbair I Neb 1.25 Transpules 2.5ml?

It is not recommended to use Salbair I Neb 1.25 Transpules 2.5ml along with other medicines, such as anticholinergic, beta-adrenergic agents, beta-blockers, diuretics, digoxin, MAO inhibitors or anti-depressants.

Q. Will Salbair I Neb 1.25 Transpules 2.5ml be more effective if taken in higher doses?

No, taking a higher than the recommended dose of this medicine will not make it more effective, rather can lead to increased side effects. If the symptoms do not get relieved by the recommended doses, please consult the doctor for re-evaluation.

Q. Can the use of Salbair I Neb 1.25 Transpules 2.5ml cause sleepiness or drowsiness?

Yes, Salbair I Neb 1.25 Transpules 2.5ml may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Q. Can the use of Salbair I Neb 1.25 Transpules 2.5ml cause dry mouth?

Yes, the use of Salbair I Neb 1.25 Transpules 2.5ml can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night.

Q. What are the instructions for storage and disposal of Salbair I Neb 1.25 Transpules 2.5ml?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.