Samtica 250mg Tablet (120'S)


Samtica 250mg Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.


The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.  Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.


Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  You may be asked for regular monitoring of blood glucose level while on treatment.


Basic Information

Mechanism Of Action

Samtica 250mg Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

Pharmacokinets

The pharmacokinetic results for abiraterone acetate showed a mean for the maximum plasma concentration (Cmax) of 54.67 ± 68.30 pg/ml, and a median time to maximum concentrations (tmax) of 5.53 h (range 2.67–35.00 h).

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Samtica

Edema (swelling)

Vomiting

Decreased potassium level in blood

Decreased white blood cell count

Fatigue

Increased liver enzymes

Anemia (low number of red blood cells)

Urinary tract infection

Diarrhea

High blood pressure

Cough

Hypercholesterolemia (high cholesterol)

Joint swelling

Increased levels of blood fat

Altered blood sugar level

Contra Indications

Abiraterone acetate is contraindicated in pregnancy and should be used with caution in patients with cardiac disease.

Pregnancy Related Information

Samtica 250mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Samtica 250mg Tablet. Please consult your doctor.

Breast Feeding Related Information

Samtica 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Indications

Abiraterone is indicated for the treatment of metastatic castration-resistant prostate cancer (mCRPC) in combination with methylprednisolone 9 or prednisone.

Interactions

A product that may interact with this drug is: radium Ra 223. Other medications can affect the removal of abiraterone from your body, which may affect how abiraterone works. Examples include drugs used to treat seizures (such as carbamazepine, phenytoin, phenobarbital, primidone), St. John's wort, among others.

Typical Dosage

 Do not chew, crush or break it. Samtica 250mg Tablet is to be taken empty stomach.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Samtica 250mg Tablet treats prostate cancer that has spread to other parts of the body.

It is usually taken with another medicine called prednisolone to reduce unwanted side effects.

It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.

Always use effective birth control measures to prevent pregnancy while taking this medicine.

Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Samtica 250mg Tablet is to be taken empty stomach.

FAQs

Q. Can Samtica 250mg Tablet cure prostate cancer?

Samtica 250mg Tablet does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Samtica 250mg Tablet then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Samtica 250mg Tablet.

Q. Is Samtica 250mg Tablet a chemotherapy drug?

Samtica 250mg Tablet is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Samtica 250mg Tablet stops your body from making testosterone. This can slow down the growth of prostate cancer.

Q. Why do I need to take prednisolone with Samtica 250mg Tablet?

Your doctor will always prescribe prednisolone with Samtica 250mg Tablet. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Samtica 250mg Tablet.

Q. Does Samtica 250mg Tablet affect liver?

Samtica 250mg Tablet can cause severe liver problems. In very rare cases, Samtica 250mg Tablet may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.