Sebifin 250mg Tablet (15'S)


Sebifin Tablet can be taken with or without food. You should take it regularly as prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. If you stop taking this medicine too early, the fungus may continue to grow and the infection may return or worsen.


This medicine's most common side effects include rash, headache, nausea, and abnormal liver enzyme. These are usually mild but let your doctor know if they bother you or last more than a few days.


Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Your doctor will monitor your liver function regularly during treatment.


Basic Information

Mechanism Of Action

Sebifin Tablet is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.


Pharmacokinets

Terbinafine reaches maximal plasma concentrations (0.8 to 1.5 μg/ml) within approximately 2 hours after a single dose. Like itraconazole, terbinafine is lipophilic and penetrates keratinizing tissue extremely well, allowing it to accumulate in the nail plate in the same manner as itraconazole.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sebifin

Headache

Diarrhea

Rash

Indigestion

Abnormal liver enzyme

Itching

Taste change

Nausea

Abdominal pain

Flatulence

Contra Indications

Chronic or active liver disease.

History of an allergic reaction to oral terbinafine.

Pregnancy Related Information

Sebifin Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Sebifin Tablet. Please consult your doctor.


Breast Feeding Related Information

Sebifin Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Indications

Terbinafine granules are used to treat fungal infections of the scalp. Terbinafine tablets are used to treat fungal infections of the toenails and fingernails. Terbinafine is in a class of medications called antifungals. It works by stopping the growth of fungi.

Interactions

Some products that may interact with this drug include: warfarin, drugs affecting liver enzymes that remove terbinafine from your body (such as amiodarone, cimetidine, rifampin, azole antifungals such as fluconazole/ketoconazole), drugs removed from your body by certain liver enzymes (such as tricyclic antidepressants,

Typical Dosage

Do not chew, crush or break it. Sebifin Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Sebifin Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Sebifin Tablet helps treat fungal infections of the skin and nails.

Do not skip any doses and finish the full course of treatment even if you feel better.

Treatment may be needed for 2 to 6 weeks for skin infections and 6 weeks to 6 months for nail infections.

Your doctor may monitor your liver function regularly during treatment. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sebifin Tablet may be taken with or without food, but it is better to take it at a fixed time.

Avoid Sebifin Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.

FAQs

Q. Can Sebifin Tablet be safe for use in patients with liver cirrhosis?

Oral intake of Sebifin Tablet is not recommended in patients with chronic or active liver disease. Your doctor may prescribe a liver function test to check whether the liver is functioning effectively or not. This is done because the medicine gets metabolized by liver enzymes and any inefficiency in liver function can lead to increased levels of the medication in the blood, resulting in increased side effects and toxicity. Therefore, it is important to inform your doctor if you have any liver disease or cirrhosis. Also, inform your doctor about the medicines you may be taking as taking Sebifin Tablet with another medicine can lead to liver toxicity and Sebifin Tablet by acting on the liver enzymes can change the levels of other drugs. Your doctor may suggest periodic monitoring (after 4-6 weeks of treatment) of liver function test and make dose adjustments accordingly.

Q. Does Sebifin Tablet cause any skin reactions?

Yes, sensitive individuals may develop skin reactions while using Sebifin Tablet. There are rare reports of people developing serious skin/hypersensitivity reactions like Stevens-Johnson syndrome, toxic epidermal necrolysis, and other severe skin reactions with Sebifin Tablet. Therefore, do not take this medication without consulting your physician. And, in case you encounter any type of skin reaction or rashes, stop the medication immediately and report to the doctor.

Q. Is Sebifin Tablet effective?

Sebifin Tablet is effective as an anti fungal medicine if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop taking this medicine too early, the fungus may continue to grow and the infection may return or worsen.

Q. How long do I need to take Sebifin Tablet?

The usual duration of treatment for Tinea pedis (fungal infection in the foot), Tinea corporis (ringworms), and Tinea cruris (fungal infection in the groin) is about 2 to 4 weeks. The duration may sometimes be extended to 6 weeks. For fungal infections of nails, the duration of treatment usually varies from 6 to 12 weeks. For fingernail fungal infections it may take 6 weeks whereas toenail fungal infection may take about 12 weeks. However, the exact duration of the therapy is decided by the doctor depending upon the type of infection, the site of infection, and the patient’s response to the therapy.