Manufacturer: Cipla Ltd
Salt Composition : Mycophenolate mofetil(500mg)
The amount of Seromune 500 Tablet you take and how often you take it depends on the type of transplant you have. Follow your doctor’s instructions on this. Take it on an empty stomach, at least 1 hour before or 2 hours after a meal, unless your doctor suggest otherwise. Swallow it as a whole, do not crush, chew, or break it. Take the medicine regularly to get maximum benefit and keep taking it even when you feel well. The treatment will continue for as long as you need it to prevent rejection.
The most common side effects of this medicine include nausea, vomiting, diarrhea, stomach pain, headache, high blood pressure, and changes in the number of white blood cells. You may catch more infections than usual as medicine suppresses the immune system. There is also an increased risk of developing some cancers for this reason. To reduce your risk of skin cancer, limit your exposure to the sun and use sunscreen. There is a long list of potential side effects of this medicine. You should ask your doctor about them and what signs to look out for because some of them can be serious and need urgent medical attention.
Seromune 500 Tablet can cause birth defects and abortion so do not take it if you are pregnant, planning to become pregnant, or breastfeeding. You should talk to your doctor before taking this medicine if you have any signs of infection or if you have any unexpected bruising or bleeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by, this medicine. You will have regular tests to check for any changes in the number of your blood cells and the amount of sugar and cholesterol in your blood.
Seromune 500 Tablet is an immunosuppressant. It reduces the action of the body's own defense system (the immune system) and prevents rejection of the transplanted organ.
Mycophenolate mofetil is rapidly absorbed in the small intestine. The maximum concentration of its active metabolite, MPA, is attained 60 to 90 minutes following an oral dose. The average bioavailability of orally administered mycophenolate mofetil in a pharmacokinetic study of 12 healthy patients was 94%.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Seromune
Nausea
Vomiting
Diarrhea
Abdominal pain
Headache
High blood pressure
Decreased white blood cell count (neutrophils)
Fungal infection
Low blood platelets
Anemia (low number of red blood cells)
Skin cancer
Bacterial infection
Hypercholesterolemia (high cholesterol)
Viral infection
Electrolyte imbalance
Gout
Weight loss
Tremors
Convulsion
Tumor
Contraindicated in patients with a hypersensitivity to mycophenolate mofetil, mycophenolic acid or any component of the drug product. With other immunosuppressive treatments, patients treated with mycophenolate are at increased risk of developing lymphomas, and other malignancies, particularly of the skin.
Seromune 500 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Seromune 500 Tablet does not cause any harmful side effects.
Seromune 500 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Mycophenolate mofetil is indicated in combination with other immunosuppressants to prevent the rejection of kidney, heart, or liver transplants in adult and pediatric patients ≥3 months old.
Drug-Drug interactions: MYCOPHENOLATE MOFETIL may interact with an immunosuppressant (azathioprine), antiviral medications (aciclovir and ganciclovir), a medication used to treat tuberculosis (rifampicin), antacids such as proton pump inhibitors, medications used to treat chronic kidney failure such as phosphate binders, and an antibiotic (norfloxacin+metronidazole).
Drug-Dood interactions: Avoid alcohol consumption as it may worsen the condition by increasing the risk of side effects.
Drug-Disease interactions: MYCOPHENOLATE MOFETIL should be used with caution in patients with liver or kidney disease, stomach ulcers, chronic infections and phenylketonuria.
Drug-Drug Interactions Checker List:
AZATHIOPRINE
ACICLOVIR
GANCICLOVIR
RIFAMPICIN
NORFLOXACIN+METRONIDAZOLE
Do not chew, crush or break it. Seromune 500 Tablet is to be taken with food.
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
Your doctor has prescribed Seromune 500 Tablet to stop your body from rejecting a transplanted organ (e.g. kidney, heart or liver).
It may take 6 to 12 weeks for Seromune 500 Tablet to start working. Keep taking it as prescribed.
It may cause birth defects so birth control is required in females with reproductive potential.
It makes you more susceptible to getting infections. Avoid contact with people who have an infection. Consult your doctor immediately if you develop a sore throat, high temperature, any other signs of infections.
Protect yourself from direct sunlight by wearing protective clothing and applying a sunscreen with a high sun protection factor (SPF).
Take it with food to minimize possible side effects like nausea and stomach pain.
Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throat, mouth ulcers, or fever.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Seromune 500 Tablet is to be taken with food.
Q. Can Seromune 500 Tablet cause cancer?
Seromune 500 Tablet may increase your chances of certain cancers like skin cancer and lymphoma (cancer of the lymph system). When outside, avoid unnecessary or prolonged exposure to sunlight, wear protective clothing, and apply sunscreen. Call your doctor if you experience a new skin sore or bump, a change in the size or color of a mole, a brown or black skin lesion (sore) with uneven edges or a sore whose one part does not look like the other, skin changes, sores that do not heal. Also, inform the doctor if you experience unexplained fever, tiredness that does not go away, weight loss, or pain or swelling in the neck, groin, or armpits.
Q. Why has my doctor given me Seromune 500 Tablet after I have had a kidney transplant?
Seromune 500 Tablet is an immunosuppressant. Seromune 500 Tablet has been prescribed to you to help your body accept the donor's kidney. It does so by working on the cells of your immune system, which fight with any foreign substance and reject its presence. This helps in making the transplanted organ more acceptable to your body.
Q. Is Seromune 500 Tablet a steroid or chemotherapy medicine? Can it cause hair loss?
Seromune 500 Tablet is neither a steroid nor a chemotherapy medicine. It is an immunosuppressant which means that it acts on your immune system to suppress or weaken it so that your body does not reject the donated organ of another person. Hair loss is a common side effect of Seromune 500 Tablet.
Q. Do I need any special tests while taking Seromune 500 Tablet?
Since Seromune 500 Tablet can affect blood count and affect the kidneys and liver, your doctor will ask you to have a blood test before you start the treatment. Once the treatment starts, your doctor will suggest you take regular blood tests to check for any changes in the blood. These blood tests will help monitor your response to the medicine and the development of any side effects.
