Manufacturer: Torrent Pharmaceuticals Ltd
Salt Composition : Sofosbuvir(400mg)
Sofocruz Tablet should be taken in the prescribed dose and duration. It can be taken with or without food, but take it at the same time daily. It is advised not to consume more than the recommended dose. It is important to inform your doctor if you have any health conditions such as liver or kidney disease. It is harmful to consume alcohol along with this medicine, so it is advised to limit or avoid alcohol. The course of the medicine should be completed for better results.
The common side effects of this medicine are tiredness and headache. You should drink plenty of fluid and eat a healthy diet to prevent or overcome the side effects. Before taking the medicine, inform your doctor if you are taking any other medicines or supplements.
Sofocruz Tablet is a combination of two antiviral medicines: Ledipasvir and Sofosbuvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.
Pharmacokinetics. Sofosbuvir is only administered orally. The peak concentration after oral administration is 0.5–2 hours post-dose, regardless of initial dose. Peak plasma concentration of the main circulating metabolite GS-331077 occurs 2–4 hours post-dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sofocruz
Tiredness
Headache
Hypersensitivity.
Pregnancy or planning pregnancy, including men whose female partners are pregnant/planning to get pregnant.
CrCl less than 50 mL/min.
Pancreatitis.
Hemoglobinopathies (e.g., thalassemia major, sickle cell anemia)
Coadministration with diagnosing.
Sofocruz Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is not known whether it is safe to consume alcohol with Sofocruz Tablet. Please consult your doctor.
Sofocruz Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Sofosbuvir is indicated for the treatment of chronic hepatitis C infection as a component of a combination antiviral treatment regimen.
Drug-Drug Interaction: SOFOSBUVIR may interact with anticonvulsants (oxcarbazepine, carbamazepine, phenytoin, phenobarbital), wakefulness-promoting agents (modafinil), antibiotics (rifapentine, rifabutin, rifampin), anti-HIV drug (tipranavir) and medicine used to treat irregular heartbeats (amiodarone).
Drug-Food Interaction: Avoid taking SOFOSBUVIR with St. John’s wort (Hypericum perforatum) or a product containing St. John’s wort (herbal medicine used to treat depression).
Drug-Disease Interaction: If you have diabetes or liver problems other than hepatitis C (if you are awaiting liver transplantation), inform your doctor before taking SOFOSBUVIR.
Drug-Drug Interactions Checker List:
OXCARBAZEPINE
CARBAMAZEPINE
PHENYTOIN
PHENOBARBITAL
MODAFINIL
RIFABUTIN
RIFAMPICIN
TIPRANAVIR
AMIODARONE
Do not chew, crush or break it. Sofocruz Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Sofocruz Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Sofocruz Tablet is used for the treatment of chronic hepatitis C virus (HCV) infection.
Take it with food, preferably at the same time everyday.
You will usually need to take this medicine every day for either 12 or 24 weeks.
Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you.
Sofocruz Tablet may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly.
Do not stop taking this medicine without your doctor’s advice.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sofocruz Tablet may be taken with or without food, but it is better to take it at a fixed time.
