Manufacturer: Natco Pharma Ltd
Salt Composition : Sorafenib(200mg)
Sorafenat 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Sorafenat 200mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Sorafenib is a small lipophilic molecule with low-solubility and high permeability. After oral administration, it is rapidly absorbed from the gastrointestinal tract and reaches the liver via the portal vein.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sorafenat
Fatigue
Nausea
Loss of appetite
Diarrhea
Abdominal pain
Hair loss
Weight loss
Rash
Painful blisters on hands and feet
If you have a history of serious hypersensitive reactions to Sorafenib or other similar medications. Serious reactions require immediate emergency treatment with supportive measures.
If you are using other types of anti-cancer medications such as carboplatin or paclitaxel.
If you are having a sudden heart condition such as heart attack, congestive heart failure, or any cardiovascular event.
If you are experiencing severe bleeding or have a history of a bleeding disorder.
If you have a history of high blood pressure. Monitor blood pressure weekly during the first 6 weeks and regularly thereafter.
If you have severe or persistent skin conditions such as Stevens-Johnson syndrome and toxic epidermal necrolysis are suspected.
If you have a stomach or intestinal perforation.
If you have a heart rhythm disorder such as QTc prolongation. Regular monitoring is required for people who are at risk.
If you are diagnosed with liver failure due to medications.
If you are currently expecting or planning to get pregnant.
Sorafenat 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Sorafenat 200mg Tablet. Please consult your doctor.
Sorafenat 200mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Sorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma. In the US, it is also indicated for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma that is refractory to radioactive iodine treatment.
Drug-Drug Interaction: SORAFENIB may have interaction with anti-cancer medicine (Sorafenib and Paclitaxel), antibiotics (Neomycin), anti-seizure medicine (carbamazepine, phenytoin), an antacid (Omeprazole).
Drug-Food Interaction: The absorption of SORAFENIB gets reduced in presence of food. This is why it is suggested to take SORAFENIB on an empty stomach or 1 or 2 hours after a meal. Additionally, an individual should avoid grapefruit juice as it may increase the amount of drug in the bloodstream.
Drug-Disease Interaction: Do not take SORAFENIB if you have squamous cell lung cancer.
Drug-Drug Interactions Checker List:
SORAFENIB
PACLITAXEL
NEOMYCIN
CARBAMAZEPINE
PHENYTOIN
OMEPRAZOLE
Do not chew, crush or break it. Sorafenat 200mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Sorafenat 200mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Sorafenat 200mg Tablet is used in the treatment of liver, kidney, and thyroid cancer.
Take it without food, or with a low fat meal and a full glass of water.
Take it at the same time everyday to maintain consistent levels in your body.
Women who could get pregnant should use a reliable method of contraception to prevent pregnancy while taking this medicine.
Your doctor may regularly monitor your blood pressure while you are taking this medicine.
Inform your doctor if you get a skin rash, or any pain, swelling, and redness of your hands and feet while you are taking this medicine.
Do not change the dose or discontinue use without consulting your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sorafenat 200mg Tablet is to be taken empty stomach.
Q. How is Sorafenat 200mg Tablet administered?
Sorafenat 200mg Tablet is an oral medicine and you should take it exactly as per your doctor’s advice. It can be taken without food or with low to moderate fat meal. It should not be taken with high-fat meal which will make Sorafenat 200mg Tablet less effective. If you are taking high-fat meal, take Sorafenib 1 hour before or two hours after high-fat meal.
Q. For how long do I need to take Sorafenat 200mg Tablet?
If Sorafenat 200mg Tablet suits you well, then you should continue taking it for the duration suggested by the doctor. However, if you experience any side effect that bothers you, talk to your doctor immediately.
Q. Do I need to take a treatment along with Sorafenat 200mg Tablet for it to work?
Sorafenat 200mg Tablet is used as a monotherapy, that is, it is a medicine which is used alone rather than in combination with other treatments like radiotherapy or chemotherapy.
Q. How do I know if I am responding to Sorafenat 200mg Tablet?
While receiving treatment with Sorafenat 200mg Tablet, your doctor will most likely recommend regular scans to monitor the size of the tumor. You may also need to get regular blood tests to see if the deranged liver or kidney functions have improved or not.
