Susten 400mg Tablet SR (10'S)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Susten SR 400 Tablet is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).  It should be taken with food. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well. 



Basic Information

Mechanism Of Action

Susten 400 MG Tablet SR has a similar action to the female hormone (chemical messenger) progesterone. It is used in the treatment of irregular menstruation caused due to an imbalance of progesterone hormone in your body.

Pharmacokinets

Progesterone is used by the sublingual route at dosages of 50 to 150 mg three to four times per day. A single 100 mg sublingual dose of Luteina has been found to reach mean peak progesterone levels of 13.5 ng/mL after 1 to 4 hours, with an elimination half-life of about 6 to 7 hours.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Susten

Hot flushes

Serve side effects of Susten

Abdominal pain

Sleepiness

Absence of menstrual periods

Itching

Flatulence

Nausea

Depression

Breast tenderness

Abnormal vaginal bleeding

Altered menstrual cycle

Edema (swelling)

Change in body weight

Changes in cervical secretion

Cholestatic jaundice

Injection site reactions (pain, swelling, redness)

Red spots or bumps

Acne

Hair loss

Excessive hair growth on face

Anaphylactic reaction

Fever

Insomnia (difficulty in sleeping)

Soreness

Diarrhea

Vaginal irritation

Vaginal dryness

Dementia

Deep vein thrombosis (blood clot in the legs)

Myocardial infarction

Stroke

Pulmonary embolism

Breast cancer

Contra Indications

breast cancer

diabetes

excessive fat in the blood

porphyria

overweight

depression

a migraine headache

a clot in the small veins that carry blood to or from the retina of the eye

high blood pressure

a heart attack

coronary artery disease

a clot in the lung

a stroke

obstruction of a blood vessel by a blood clot

thrombophlebitis, an inflamed vein due to a blood clot

blood clot in a deep vein of the extremities

at risk for formation of blood clots

liver problems

visible water retention

bedridden patient or one unable to move around freely

Pregnancy Related Information

Susten SR 400 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Susten SR 400 Tablet. Please consult your doctor.


Breast Feeding Related Information

Susten SR 400 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Progesterone is used to help prevent changes in the uterus (womb) in women who are taking conjugated estrogens after menopause. It is also used to properly regulate the menstrual cycle and treat unusual stopping of menstrual periods (amenorrhea) in women who are still menstruating.

Interactions

bazedoxifene/conjugated estrogens.

conjugated estrogens.

conjugated estrogens, vaginal.

doxorubicin.

doxorubicin liposomal.

ruxolitinib.

Typical Dosage

Do not chew, crush or break it. Susten SR 400 Tablet is to be taken with food.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Susten SR 400 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Susten SR 400 Tablet is a natural progesterone available as a micronized formulation which helps in better absorption of this medicine.

It is used as a part of hormone replacement therapy generally in combination with an estrogen.

It may also be used in the treatment of problems related to menstrual periods such as amenorrhea (absence of periods).

It also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.

It should be taken with food.

It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Susten SR 400 Tablet is to be taken with food.


FAQs

Q. What is Susten SR 400 Tablet?

Susten SR 400 Tablet is a type of progesterone hormone which is extracted from plants, but its property matches with the human progesterone. This medicine undergoes a process called micronization where the size of the natural progesterone is reduced. The small size of the progesterone particles enhances its dissolution and absorption. This provides better availability of Susten SR 400 Tablet in the body and decreases its side effects.

Q. What is Susten SR 400 Tablet used to treat?

Susten SR 400 Tablet is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in women who have had their menses before). It is used to support pregnancy, prevent premature labor, and treat bleeding disorders that may occur before menopause. It may be used as a part of fertility treatment and may be given as hormone replacement therapy after menopause. It is also given to relieve symptoms of premenstrual syndrome and painful bleeding like in dysfunctional uterine bleeding.

Q. Can you take Susten SR 400 Tablet every day?

Yes, Susten SR 400 Tablet can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.

Q. Does Susten SR 400 Tablet cause weight gain?

Yes, taking Susten SR 400 Tablet may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Susten SR 400 Tablet is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.

Q. Is Susten SR 400 Tablet safe?

Yes, Susten SR 400 Tablet is safer as compared to the normal synthetic progesterone. Its smaller size helps the body absorb it easily and reduces the side effects like fluid retention, reduction of HDL cholesterol levels, headaches and mood disturbance.

Q. How is progesterone beneficial for fertility and pregnancy?

Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. Susten SR 400 Tablet (natural micronized form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.