Manufacturer: Pfizer Ltd
Salt Composition : Sunitinib(12.5mg)
Sutent 12.5mg Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, weakness and weight loss are some common side effects of this medicine. The doctor may advise for regular monitoring of blood pressure and thyroid gland function while taking this medicine. It may decrease blood sugar levels. In fact, the levels can decrease to the extent that the patient may faint. So, if you are diabetic then it is important to check your blood sugar levels regularly. Additionally, you should also consult the doctor if the dose of anti-diabetic medicines needs to be adjusted. This medicine may affect wound healing time, so be careful while shaving, cutting fingernails or using sharp objects.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or bleeding disorder. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Sutent 12.5mg Capsule is an anti-cancer medication. It works by binding and blocking certain cell surface protein (tyrosine kinase) responsible for the propagation of cancer growth. It also restricts the growth of new blood vessels within the tumor. This is how it prevents the proliferation of malignant cancers.
Maximum plasma concentrations (Cmax) of sunitinib are generally observed between 6 and 12 hours (Tmax) following oral administration. Food has no effect on the bioavailability of sunitinib.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sutent
Hand-foot syndrome
Bleeding disorder
Low blood platelets
Decreased appetite
Nausea
Vomiting
Weakness
Abdominal pain
Indigestion
High blood pressure
Diarrhea
Stomatitis (Inflammation of the mouth)
Taste change
lefamulin will increase the level or effect of sunitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lefamulin is contraindicated with CYP3A substrates know to prolong the QT interval. sunitinib and posaconazole both increase QTc interval.
Sutent 12.5mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Sutent 12.5mg Capsule. Please consult your doctor.
Sutent 12.5mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Bleeding gums.
bloating or swelling of the face, arms, hands, fingers, lower legs, or feet.
blurred vision.
chest pain.
chills.
confusion.
constipation.
coughing up blood.
The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Ajmaline. The metabolism of Sunitinib can be decreased when combined with Albendazole. The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Albiglutide.
Sutent 12.5mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Sutent 12.5mg Capsule, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take this medicine in the dose and duration as advised by your doctor. Sutent 12.5mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
Q. How should I take Sutent 12.5mg Capsule?
You should take Sutent 12.5mg Capsule exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Sutent 12.5mg Capsule, as the chances of side effects may be more.
Q. Does Sutent 12.5mg Capsule have any effect on skin and hair?
During treatment with Sutent 12.5mg Capsule, your skin may get lighter and there may be hair loss. Also, patient may experience dryness, thickness or cracking of the skin, blisters, or rashes on the palms and soles. But, these side effects are reversible and go away once the medicine is stopped. Sutent 12.5mg Capsule may also cause serious skin reactions such as severe rash or rapidly spreading skin ulceration which could be fatal. Therefore, inform your doctor immediately if symptoms of infection occur around a skin injury. Let your doctor know if you have fever, pain, redness, swelling, or drainage of pus or blood.
Q. What is the most important thing I need to know about Sutent 12.5mg Capsule?
Sutent 12.5mg Capsule can cause serious side effects such as severe liver problems that can lead to death. Therefore, tell your doctor right away if you experience itching, yellow eyes or skin, dark urine or pain or discomfort in the right upper stomach area. Your doctor will get blood tests done to check your liver function before and during treatment with Sutent 12.5mg Capsule. In case you develop liver problems, your doctor may stop the medicine temporarily or permanently.
Q. Are generics available for Sutent 12.5mg Capsule? How does Sutent 12.5mg Capsule work?
There are no generics available for Sutent 12.5mg Capsule. Sutent 12.5mg Capsule blocks an enzyme which promotes the growth and spread of cancer cells. This enzyme is called protein kinase and is present on the surface of cancer cells. Blocking this enzyme stops the spread of cancer. Examples of other protein kinase inhibitors are erlotinib, gefitinib, lapatinib, vemurafenib and dasatinib.
