Manufacturer: Emcure Pharmaceuticals Ltd
Salt Composition : Tranexamic Acid(500mg), Ethamsylate(250mg)
Sylate T 250 mg/250 mg Tablet is a combination medicine used in the treatment of heavy menstrual bleeding. It works by preventing the breakdown of blood clots and controls excessive bleeding. It also increases the ability of platelets to stick together and form blood clots.
You can take Sylate T 250 mg/250 mg Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Take this medicine in the dose and duration advised by the doctor and if you have missed a dose, take it as soon as you remember. Remember to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.
The most common side effects of this medicine include nausea, stomach pain, headache, nasal congestion, sinus pain, sinus inflammation, rash, tiredness, and musculoskeletal (bone, muscle or joint) pain. It may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. It is advised to consult with your doctor if you do not notice any changes in periods after 3 consecutive periods.
Before taking it, let your doctor know if you have any kidney problems or vaginal bleeding disorder. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking. You might be asked for eye check-ups while taking this medicine.
Tranexamic acid is a synthetic derivative of the amino acid lysine and binds the 5 lysine binding sites on plasminogen. This inhibits plasmin formation and displaces plasminogen from the fibrin surface. It may also directly inhibit plasmin and partially inhibit fibrinogenolysis at higher concentrations
Ethamsylate acts on the first step of hemostasis by improving platelet adhesiveness and restoring capillary resistance. Recent studies showed that ethamsylate promotes P-selectin-dependent, platelet adhesive mechanisms. Finally, we compare ethamsylate with other recent hemostatic agents
Tranexamic acid 1 g was given intravenously to three healthy volunteers. Plasma concentrations decayed in three monoexponential phases. Most elimination took place during the first eight hours, giving an apparent elimination half-life of approximately two hours. Plasma clearance ranged between 110-116 ml/min.
It increases platelet adhesiveness and capillary vascular wall resistance, thereby reducing capillary exudation and blood loss. Synonym: ethamsylate. Pharmacokinetics: Absorption: Slowly and completely absorbed from the gastrointestinal tract.
Nausea
Stomach pain
Diarrhea
Headache
Nasal congestion (stuffy nose)
Sinus pain
Sinus inflammation
Rash
Tiredness
Musculoskeletal (bone, muscle or joint) pain
Anemia (low number of red blood cells)
increased risk of blood clotting.
fluid accumulation in the brain.
a clot in the small veins that carry blood to or from the retina of the eye.
a heart attack.
acute blood clot in a blood vessel supplying the lungs.
heart valve disease.
Hypersensitivity to ethamsylate and porphyria are contraindications for its use. Nausea, headache, rashes, transient hypotension
Information regarding the use of Sylate T 250 mg/250 mg Tablet during pregnancy is not available. Please consult your doctor.
Sylate T 250 mg/250 mg Tablet may cause excessive drowsiness with alcohol.
Information regarding the use of Sylate T 250 mg/250 mg Tablet during breastfeeding is not available. Please consult your doctor.
Tranexamic acid (sometimes shortened to txa) is a medicine that controls bleeding. It helps your blood to clot and is used for nosebleeds and heavy periods. If you're having a tooth taken out, using tranexamic acid mouthwash can help stop bleeding
Hemorrhage from small blood vessels. Menorrhagia. Treatment and prevention of periventricular hemorrhage in low birth-weight neonates
Some products that may interact with this drug include: "blood thinners" (anticoagulants such as warfarin, heparin), drugs that prevent bleeding (including factor IX complex, anti-inhibitor coagulant concentrates), estrogens, hormonal birth control (such as pills, patch, ring), tibolone, tretinoin
Drug-Drug Interaction: ETAMSYLATE interact with birth control pill, it may increase your chance of having a blood clot, heart attack, or stroke.
Drug- Food Interaction: Intake of excessive alcoholic beverages may increase the chance of more side effects.
Do not chew, crush or break it. Sylate T 250 mg/250 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Sylate T 250 mg/250 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Sylate T 250 mg/250 mg Tablet is prescribed to reduce excessive bleeding during menstruation.
Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
If you get diarrhea while taking this medicine, consult your doctor immediately.
Along with taking Sylate T 250 mg/250 mg Tablet you can use a heating pad or try gentle massage and relaxation techniques to get relief during periods.
Inform your doctor if there is no improvement in your bleeding after using this medicine for three consecutive periods.
Inform your doctor if you have any bleeding disorders.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sylate T 250 mg/250 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can the use of Sylate T 250 mg/250 mg Tablet cause diarrhea?
Yes, the use of Sylate T 250 mg/250 mg Tablet can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists. Do not take any other medicine without consulting a doctor.
Q. Can I use oral contraceptives while using Sylate T 250 mg/250 mg Tablet?
No, do not use oral contraceptives while using Sylate T 250 mg/250 mg Tablet. Use of oral contraceptives along with this medicine increases the chance of serious complications.
Q. Will a higher than the recommended dose of Sylate T 250 mg/250 mg Tablet be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.
Q. What are the instructions for storage and disposal of Sylate T 250 mg/250 mg Tablet?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
