Manufacturer: Natco Pharma Ltd
Salt Composition : Tenofovir Alafenamide(25mg)
Tafnat Tablet should be used in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body. It is important to keep taking them until your doctor tells you it is safe to stop.
Common side effects of this medicine include headache, diarrhea, nausea, joint pain, abdominal pain, and indigestion. Please consult your doctor if it persists for a longer duration. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.
Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.
Tafnat Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.
TAF exhibits greater stability in the intestine and plasma as compared to tenofovir disoproxil fumarate (TDF), providing greater loading into lymphoid cells, including peripheral blood mononuclear cells, before converting to TFV, which is subsequently phosphorylated into the active form, TFV diphosphate.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tafnat
Headache
Diarrhea
Nausea
Fatigue
Abdominal pain
Cough
Back pain
Indigestion
Joint pain
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, HIV infection, other liver problems (such as hepatitis C, cirrhosis), bone problems (such as bone disease, bone loss/osteoporosis, weak/broken bones), disease of the pancreas (pancreatitis).
Tafnat Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is not known whether it is safe to consume alcohol with Tafnat Tablet. Please consult your doctor.
Tafnat Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Tenofovir alafenamide (TAF) is a prodrug of tenofovir. The antiviral properties of tenofovir are due to its inhibition of HBV polymerase, which, in turn, inhibits DNA synthesis and viral replication. TAF is indicated for the treatment of chronic hepatitis B in adults with compensated liver disease.
Drug-Drug Interactions: TENOFOVIR ALAFENAMIDE may interact with an antibiotic (e.g. tobramycin, pentamidine, vancomycin), antifungal medicines (e.g. amphotericin B), antiviral disease (e.g. foscarnet, ganciclovir), medications used to treat hepatitis B virus (e.g. adefovir), pain killer (e.g. ibuprofen). The relevance of a particular drug interaction varies from person to person.
Drug-Food Interactions: Avoid drinking alcohol. Consuming alcohol while using TENOFOVIR ALAFENAMIDE may worsen the condition.
Drug-Disease Interactions: TENOFOVIR ALAFENAMIDE should not be used in patients with bone disease or severe liver or kidney diseases.
Drug-Drug Interactions Checker List:
TOBRAMYCIN
PENTAMIDINE
VANCOMYCIN
AMPHOTERICIN B
FOSCARNET
GANCICLOVIR
ADEFOVIR
IBUPROFEN
Do not chew, crush or break it. Tafnat Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Tafnat Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Tafnat Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
In combination with other medicines, it is used for the treatment of HIV infections.
Take it with food, as this increases the absorption of the medicine into the body.
Tafnat Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
You may still develop infections or other illnesses associated with viral infection while taking this medication.
You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tafnat Tablet is to be taken with food.
Q. Does Tafnat Tablet prevent passing of HIV-1 and HBV to others?
In case of HIV-1 infection, Tafnat Tablet may reduce the risk of passing the virus to others, but the chances of infecting others still persist. However, in case of HBV infection, Tafnat Tablet has not proven to reduce risk of transferring the virus to others. Therefore, the patients of both HIV-1 infection and HBV infection should practice safe sex and should not share dirty needles.
Q. Is Tafnat Tablet safe?
Tafnat Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. How should I take Tafnat Tablet?
You should take Tafnat Tablet in the dose and duration advised by your doctor. Tafnat Tablet works best when taken with meals or just afterwards. However, taking it without food does not reduce its effectiveness. If you have any doubts, consult your doctor.
Q. For how long do I need to take Tafnat Tablet for HBV infection?
Duration of treatment will depend on the severity of HBV infection. You will need to take periodic blood tests to keep a check on the viral load and number of T cells. Your doctor will then decide the duration of the medicine accordingly. In some cases, treatment is required life long.
