Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Tacrolimus(0.1% w/w)
Takfa Forte Ointment is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.
It is a safe medicine with few side effects, but you may get an application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.
Tacrolimus works by suppressing the skin’s immune system, thus reducing allergic reactions like redness, swelling, itching and relieving eczema.
Tacrolimus is completely metabolised prior to elimination. The mean disposition half-life is 12 hours and the total body clearance based on blood concentration is approximately 0.06 L/h/kg. The elimination of tacrolimus is decreased in the presence of liver impairment and in the presence of several drugs.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Takfa
Application site reactions (burning, irritation, itching and redness)
Diarrhea
Increased glucose level in blood
Increased thirst
Kidney damage
Liver damage
Nausea
Stomach pain
a bad infection.
cancer or malignancy.
diabetes.
low amount of magnesium in the blood.
low amount of calcium in the blood.
high levels of potassium in the blood.
low amount of potassium in the blood.
high blood pressure.
Takfa Forte Ointment may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Takfa Forte Ointment is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Immediate-release formulations of tacrolimus are indicated for the prophylaxis of organ rejection in adult and pediatric patients receiving allogeneic liver, kidney, heart, or lung transplants, in combination with other immunosuppressants.
diabetes mellitus.
hepatic dysfunction.
infections.
QT interval prolongation.
renal dysfunction.
hyperkalemia.
hypertension.
Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.
Store below 30°C
If you miss a dose of Mavtac Forte Ointment, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Takfa Forte Ointment is effective at treating eczema (atopic dermatitis) when other treatment options have failed.
It works by decreasing itching, redness, and skin rashes.
Apply thinly, to affected areas of skin only. Clean the affected area and dry well before applying Takfa Forte Ointment. Avoid contact with water after application.
Inform your doctor if there's no improvement even after two weeks of treatment, or if the skin gets worse.
Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
Stop using Takfa Forte Ointment and consult your doctor if your eczema becomes infected.
Continuous long-term use of the ointment should be avoided. Use as prescribed by you doctor.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.
Q. What is Takfa Forte Ointment used for?
Takfa Forte Ointment is a medicine that modulates the immune system. It works on the immune system and mostly decreases its activity. It is used to treat moderate to severe eczema (atopic dermatitis) in adults who do not respond to steroids or develop side effects on using them. In atopic dermatitis, the skin’s immune system undergoes an overreaction and causes skin inflammation leading to itchiness, redness and dryness. Takfa Forte Ointment acts on the abnormal immune response and alters it, thereby relieving the skin inflammation and itchiness.
Q. What are the side effects of Takfa Forte Ointment?
Takfa Forte Ointment, when applied to the skin, may cause skin irritation, burning sensation and itching at the site of application. These are usually mild to moderate in severity and normally resolve within one week of starting the treatment. Redness is also a common manifestation along with sensation of warmth, pain, altered sensation and rash at the site of application. Using it increases the patients’ increased risk of getting inflamed or infected hair follicles, cold sores, acne and generalized herpes simplex infections.
Q. Is Takfa Forte Ointment ointment safe?
As compared to other immune-suppressing medicines, Takfa Forte Ointment has been found to be a safe and effective short-term treatment for atopic dermatitis. When applied on the affected part of the skin, its absorption to the blood and body is minimal. Hence, the side effects are less as compared to when taken through oral route.
Q. Does Takfa Forte Ointment has abuse potential?
No, Takfa Forte Ointment does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission by authorities and doctor for use.
Q. Does Takfa Forte Ointment cause cancer?
Long-term use of Takfa Forte Ointment has been found to have increased risk of lymph node tumors called lymphoma. Some studies have found that few patients who used Takfa Forte Ointment ointment or another similar medication developed skin cancer or lymphoma. Consult your doctor if you have to use Takfa Forte Ointment ointment for more than 6 weeks or if your eczema symptoms have not improved or are getting worse with time during your treatment.
Q. Is Takfa Forte Ointment a steroid?
No, Takfa Forte Ointment is not a steroid. It is a medicine which modulates the working of the immune system. It is used in the treatment of eczema, most commonly in atopic dermatitis. An advantage of Takfa Forte Ointment is that it does not cause skin thinning (atrophy) or other steroid-related side effects.
