Manufacturer: Novartis India Ltd
Salt Composition : Nilotinib(200mg)
Tasigna 200mg Capsule should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Headache, nausea, abdominal pain, and rash are very common side effects of this medicine. If you experience severe diarrhea, consult with your doctor or drink plenty of fluids while on treatment. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels and blood sugar or fat level in the body.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Tasigna 200mg Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Nilotinib is rapidly absorbed, with a peak serum concentration approximately 3 hours after dosing.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tasigna
Headache
Nausea
Abdominal pain
Rash
Itching
Hair loss
Muscle pain
Fatigue
Hypersensitivity to nilotinib or any component of the formulation; persistent QTc >48 msec, Hypokalemia, hypomagnesemia, or long QT syndrome.
Tasigna 200mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Tasigna 200mg Capsule does not cause any harmful side effects.
Tasigna 200mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Nilotinib is a kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
Drug-Drug Interaction: NILOTINIB may interact with anti-arrhythmic drugs (disopyramide, quinidine, amiodarone, sotalol, procainamide), antibiotics (clarithromycin, moxifloxacin), antimalarial drugs (chloroquine), antipsychotics (haloperidol, pimozide), opioid analgesics (methadone, fentanyl, alfentanil), anticonvulsants (phenytoin, carbamazepine, phenobarbital), blood thinner (warfarin), anti-HIV drug (rifampicin), antifungals (itraconazole, ketoconazole, voriconazole) and immunosuppressants (cyclosporine, tacrolimus, sirolimus). Inform your doctor if you are using any medicines before taking NILOTINIB.
Drug-Food Interaction: Avoid grapefruit juice, grapefruit and any supplement containing grapefruit extract while taking NILOTINIB as it may increase the amount of Nilotinib in the body and cause serious side effects. Also, NILOTINIB may interact with St. John’s wort (a herbal product used to treat depression).
Drug-Disease Interaction: Avoid taking NILOTINIB if you have low levels of magnesium or potassium in the blood or long QTc syndrome. If you have had pancreatitis, stroke or other problems due to decreased blood flow to the brain, have QTc prolongation or a family history of it, bleeding problems, irregular heartbeat, have low problems with decreased blood flow to your legs, have low levels of magnesium or potassium in blood, heart or liver problems, inform your doctor before taking NILOTINIB.
Drug-Drug Interactions Checker List:
DISOPYRAMIDE
QUINIDINE
AMIODARONE
SOTALOL
PROCAINAMIDE
CLARITHROMYCIN
MOXIFLOXACIN
CHLOROQUINE
HALOPERIDOL
PIMOZIDE
METHADONE
FENTANYL
ALFENTANIL
PHENYTOIN
CARBAMAZEPINE
PHENOBARBITAL
WARFARIN
RIFAMPICIN
ITRACONAZOLE
KETOCONAZOLE
VORICONAZOLE
CYCLOSPORINE
TACROLIMUS
SIROLIMUS
Tasigna 200mg Capsule is to be taken empty stomach.
Store below 30°C
If you miss a dose of Tasigna 200mg Capsule, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take this medicine in the dose and duration as advised by your doctor. Tasigna 200mg Capsule is to be taken empty stomach.
