Manufacturer: Glenmark Pharmaceuticals Ltd
Salt Composition : Docetaxel(80mg)
Taxuba 80 Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
The medicine works by interrupting the multiplication of cancer cells that results in cells being inactive and this leads to the death of the cancerous cells.
The pharmacokinetic profile is consistent with a three-compartment model. The area under the curve (AUC) was dose proportional following doses of 70 mg/m2 to 115 mg/m2 with infusion times of 1 to 2 hours. In vitro studies show that 94% protein bound, mainly to a1-acid glycoprotein, albumin, and lipoproteins.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Taxuba
Breathlessness
Constipation
Edema (swelling)
Infection
Loss of appetite
Muscle pain
Nail disorder
Pain
Weakness
Docetaxel Injection is contraindicated in patients who have a history of severe hypersensitivity reactions to docetaxel or to other drugs formulated with polysorbate 80. Severe reactions, including anaphylaxis, have occurred
Taxuba 80 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Taxuba 80 Injection.
Taxuba 80 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Docetaxel Injection is indicated for the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy.
infections.
edema.
eye disorder.
hepatic dysfunction.
myelosuppression.
alcoholism.
paresthesia.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Taxuba 80 Injection, consult your doctor.
Consult a doctor before taking any medicines.
Taxuba 80 Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.
Do not take Taxuba 80 Injection if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
It may cause side effects such as swelling of hands, lips, and weight gain. To reduce these side effects your doctor may suggest some medication along with this medicine called Corticosteroids.
Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Does Taxuba 80 Injection cause weight gain?
Yes, Taxuba 80 Injection may cause weight gain. It may occur due to fluid retention which may initially make your feet swell and then gradually it will spread to the whole body. Call your doctor immediately if you notice swelling of feet.
Q. How long do I have to take Taxuba 80 Injection?
You should continue to take Taxuba 80 Injection as long as your doctor advises you. The duration of treatment varies with the type of cancer you have and other factors like your response to treatment. You should usually receive your infusion once every 3 weeks.
Q. Can I drink alcohol while on Taxuba 80 Injection?
Taxuba 80 Injection injection contains alcohol because of which you may experience confusion, stumbling, becoming very sleepy, or feeling like you are drunk. This may impair your ability to drive or use machinery right after receiving it. Hence, you should avoid alcohol during Taxuba 80 Injection therapy, as it may affect you adversely.
Q. What is Taxuba 80 Injection used for?
Taxuba 80 Injection is commonly used for breast cancer, certain types of lung cancer, prostate, stomach, and head and neck cancers. It works by restricting cells from growing and multiplying.
Q. Is Taxuba 80 Injection available in pill form?
No, Taxuba 80 Injection injection comes as a liquid to be given intravenously (into a vein) by a doctor or nurse in a hospital or clinic. It is usually given over 1 hour once every 3 weeks.
Q. What blood tests are required before administration of Taxuba 80 Injection?
Your doctor will ask you to get blood tests every time you have a scheduled dose of Taxuba 80 Injection. You may be asked to have blood tests, such as hemogram and liver function tests, to ensure that you have enough blood cells and that your liver is functioning well enough to receive Taxuba 80 Injection. In case of white blood cells disturbances, you may experience associated fever or infections.
Q. Is hair loss caused by Taxuba 80 Injection irreversible?
Hair loss is a common side effect of Taxuba 80 Injection. Normal hair growth may resume after stopping Taxuba 80 Injection. However, in some cases there is permanent hair loss. Consult your doctor if you have any concerns regarding hair loss.
Q. Why is dexamethasone used with Taxuba 80 Injection?
Taxuba 80 Injection may cause fluid retention (swelling in the hands, feet, ankles and legs) as well as severe hypersensitivity reactions. To control such possibilities from occurring all patients are given corticosteroids (dexamethasone) for 3 days starting 1 day prior to Taxuba 80 Injection administration. In case of prostate cancer (metastatic castration-resistant), the recommended regimen is oral dexamethasone given at 12 hours, 3 hours, and 1 hour before the Taxuba 80 Injection infusion.
Q. What type of drug is Taxuba 80 Injection?
Taxuba 80 Injection belongs to the group of anti-cancer medicines called taxoids. It works by stopping the growth and spread of cancer cells.
