Manufacturer: Alkem Laboratories Ltd
Salt Composition : Temozolomide(250mg)
Temokem 250mg Injection is given by a nurse or a doctor. You should not self-administer this medicine. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on the severity of your condition and may change from time to time. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, constipation, headache, and fatigue. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver, and heart function during treatment with this medicine.
Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Temokem 250mg Injection is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
Temozolomide is rapidly absorbed after oral administration with almost 100% bioavailability, and its plasma pharmacokinetics is linear and predictable, both in adults and children [7–10]. Temozolomide is a pro-drug for methyl triazene (MITC), which is the final active methylating compound
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Temokem
Memory loss
Rash
Headache
Dizziness
Convulsion
Coordination disorder
Insomnia (difficulty in sleeping)
Vomiting
Weakness
Nausea
Loss of appetite
Hair loss
Fatigue
Fever
Diarrhea
Constipation
Hemiparesis (weakness on one side of the body)
Viral infection
pneumonia with a fungus called Pneumocystis jirovecii
a type of blood disorder with a decrease in all types of blood cells called pancytopenia
decreased function of bone marrow
low blood counts due to bone marrow failure
anemia
decreased blood platelets
low levels of a type of white blood cell called neutrophils
a decreased number of lymphocytes in the blood
myelodysplastic syndrome, a bone marrow disorder
abnormal liver function tests
pregnancy
a patient who is producing milk and breastfeeding
Temokem 250mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Temokem 250mg Injection. Please consult your doctor.
Temokem 250mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
TEMODAR® (temozolomide) is indicated for the treatment of adult patients with newly diagnosed glioblastoma multiforme concomitantly with radiotherapy and then as maintenance treatment.
urticaria.
hepatic impairment.
myelosuppression.
renal impairment.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Temokem 250mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Temokem 250mg Injection is given as an injection into the vein under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
Inform your doctor if you experience severe skin rash, fever, chills, headache and shortness of breath during the treatment.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
