Manufacturer: United Biotech Pvt Ltd
Salt Composition : Temozolomide(250mg)
Temotec 250mg Capsule should be taken empty stomach and at same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, constipation, headache and fatigue. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine.
Before taking it, tell your doctor if have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped.
The growth and multiplication of cells take place through DNA, a genetic material. Temozolomide works by inhibiting the growth and multiplication of cancer cells by stopping them from making DNA, resulting in cell death.
Temozolomide is rapidly absorbed after oral administration with almost 100% bioavailability, and its plasma pharmacokinetics is linear and predictable, both in adults and children [7–10]. Temozolomide is a pro-drug for methyl triazene (MITC), which is the final active methylating compound
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Temoside
Nausea
Vomiting
Constipation
Headache
Fatigue
Convulsion
Coordination disorder
Diarrhea
Dizziness
Fever
Hair loss
Hemiparesis (weakness on one side of the body)
Insomnia (difficulty in sleeping)
Loss of appetite
Memory loss
Rash
Viral infection
Weakness
pneumonia with a fungus called Pneumocystis jirovecii
a type of blood disorder with a decrease in all types of blood cells called pancytopenia
decreased function of bone marrow
low blood counts due to bone marrow failure
anemia
decreased blood platelets
low levels of a type of white blood cell called neutrophils
a decreased number of lymphocytes in the blood
myelodysplastic syndrome, a bone marrow disorder
abnormal liver function tests
pregnancy
a patient who is producing milk and breastfeeding
Temotec 250mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Temotec 250mg Capsule. Please consult your doctor.
Temotec 250mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
TEMODAR® (temozolomide) is indicated for the treatment of adult patients with newly diagnosed glioblastoma multiforme concomitantly with radiotherapy and then as maintenance treatment.
urticaria.
hepatic impairment.
myelosuppression.
renal impairment.
Temotec 250mg Capsule is to be taken empty stomach.
Store below 30°C
If you miss a dose of Temotec 250mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Temotec 250mg Capsule should be taken on an empty stomach.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
Inform your doctor if you experience severe skin rash, fever, chills, headache and shortness of breath during the treatment.
Take this medicine in the dose and duration as advised by your doctor. Temotec 250mg Capsule is to be taken empty stomach.
