Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Metformin(1000mg), Teneligliptin(20mg)
Strip of 15 Tablet Er
(Inclusive of all taxes)
Teniva-M Forte Tablet ER can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.
You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it.
This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver, or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect this one so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.
Teneligliptin in this medicine works by increasing insulin secretion from the pancreas by inhibiting the enzyme dipeptidyl peptidase 4 (DPP4), whereas Metformin decreases the production of glucose from the liver, the amount of glucose absorbed from the intestine and increases insulin sensitivity.
Metformin is rapidly distributed following absorption and does not bind to plasma proteins. No metabolites or conjugates of metformin have been identified. The absence of liver metabolism clearly differentiates the pharmacokinetics of metformin from that of other biguanides, such as phenformin.Teneligliptin is a potent, selective, and long-lasting DPP-4 inhibitor with a t½ of approximately 24 h and unique pharmacokinetic properties: it is metabolized by cytochrome P450 (CYP) 3A4 and flavin-containing monooxygenase 3 (FMO3), or excreted from the kidney in an unchanged form.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tenlip-M
Hypoglycemia (low blood glucose level)
Nausea
Vomiting
Diarrhea
Headache
Bloating
Flatulence
METFORMIN+TENELIGLIPTIN should be avoided in patients with heart diseases (congestive heart failure and myocardial infarction), vitamin B12 deficiency, alcoholism, type I diabetes, bladder cancer, oedema (fluid retention), liver disease, premenopausal anovulation, obesity (weight gain), anaemia should avoid intake of METFORMIN+TENELIGLIPTIN.
Teniva-M Forte Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Teniva-M Forte Tablet ER.
Teniva-M Forte Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
By increasing and prolonging active incretin levels, teneligliptin increases insulin release and decreases glucagon levels in the circulation in a glucose-dependent manner. Metformin improves glucose tolerance in patients with type-2 diabetes (NIDDM), lowering both basal and postprandial plasma glucose.
METFORMIN+TENELIGLIPTIN may have an interaction with medicines used to treat bacterial infections (rifampicin, tetracycline, Clarithromycin), a medicine used to treat fungal infections (fluconazole), other oral antidiabetics, medicines used to treat gout (probenecid).
Do not chew, crush or break it. Teniva-M Forte Tablet ER is to be taken with food.
Store below 30°C
If you miss a dose of Teniva-M Forte Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
Take it in addition to regular exercise and a healthy diet to lower levels of blood sugar.
Take it with food to lower your chance of having an upset stomach.
Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Teniva-M Forte Tablet ER may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Teniva-M Forte Tablet ER is to be taken with food.
Q. Is it safe to use Teniva-M Forte Tablet ER?
Yes, it is safe to use Teniva-M Forte Tablet ER if you take it for the prescribed duration and according to the dosage advised by the doctor. However, despite taking the prescribed dosage you might experience common side effects like nausea, diarrhea, vomiting, stomach upset, headache, nasal congestion, sore throat, respiratory tract infection and hypoglycemia (low blood sugar level). Hypoglycemia is relatively common in patients who are taking Teniva-M Forte Tablet ER in combination with insulin or Sulfonylurea. Inform your doctor if you experience any persistent problem while taking this medicine.
Q. Can the use of Teniva-M Forte Tablet ER lead to hypoglycemia?
The use of Teniva-M Forte Tablet ER does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over-exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.
Q. Can the use of Teniva-M Forte Tablet ER cause nausea and vomiting?
Yes, the use of Teniva-M Forte Tablet ER can cause nausea and vomiting. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without consulting a doctor.
Q. Are there any specific contraindications associated with the use of Teniva-M Forte Tablet ER?
The use of Teniva-M Forte Tablet ER should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.
Q. Can the use of Teniva-M Forte Tablet ER cause lactic acidosis?
Yes, the use of Teniva-M Forte Tablet ER can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Teniva-M Forte Tablet ER and immediately consult your doctor.
Q. Can the use of Teniva-M Forte Tablet ER lead to Vitamin B12 deficiency?
Yes, the use of Teniva-M Forte Tablet ER can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. Deficiency of B12 may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.
Q. What is the storage condition for the Teniva-M Forte Tablet ER?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
