Thiopental 500mg (Injection)

Manufacturer: Vhb Life Sciences Inc

Salt Composition : Thiopental Sodium(500mg)

₹52.90

Vial of 1 Injection

(Inclusive of all taxes)


Thiopental 500 mg Injection is an anesthetic used for inducing and maintaining unconsciousness or sleep during surgical procedures. It is also used to reduce intracranial pressure in neurosurgical patients and as an adjunct for the control of fits during or following inhalation anesthesia or local anesthetics. It should only be administered by a trained healthcare professional. 



Basic Information

Mechanism Of Action

This medicine works by altering the action of certain natural substances, which in turn induces unconsciousness and sedation.

Pharmacokinets

In anaesthesiology the pharmacokinetics of thiopental are described as linear; when doses and duration of treatment increase, nonlinear pharmacokinetics occur because of the saturation and/or the induction of the metabolism.

Side Effects

Major & minor side effects for Thiopental 500 mg Injection

Weak/shallow breathing

Slow heartbeat

Chills or shivering

Wheezing

Chest tightness

Drowsiness

Cough

Sneezing

Low blood pressure


Contra Indications

 Thiopental should be used with caution in cases of liver disease, Addison's disease, myxedema, severe heart disease, severe hypotension, a severe breathing disorder, or a family history of porphyria. Co-administration of pentoxifylline and thiopental causes death by acute pulmonary edema in rats.

Pregnancy Related Information

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.


Breast Feeding Related Information

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.


Indications

(Thiopental Sodium for Injection, USP) is indicated (1) as the sole anesthetic agent for brief (15 minute) procedures, (2) for induction of anesthesia prior to administration of other anesthetic agents, (3) to supplement regional anesthesia, (4) to provide hypnosis during balanced anesthesia with other agents .

Interactions

The risk or severity of CNS depression can be increased when Thiopental is combined with Acetazolamide. The risk or severity of adverse effects can be increased when Acetophenazine is combined with Thiopental. The metabolism of Thiopental can be increased when combined with Acetylsalicylic acid.

Storage Requirements

 Store below 30°C

Effects Of Missed Dosage

Since this medicine is usually administered by a qualified healthcare professional before and during a surgical procedure in the clinical/hospital setting, the likelihood of a missed dose is very low.


Effects Of Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.


Expert Advice

This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine


How To Use

Anesthesia

This medicine is used to induce and maintain anesthesia during surgical procedures.

Seizures

This medicine is used as an adjunct for the control of fits or convulsive episodes during or following inhalation anesthesia or local anesthetics.

Coma induction

This medicine is used to reduce intraoperative rises of intracranial pressure in neurosurgical patients if adequate ventilation is given