Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Tetrabenazine(25mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Ticstop Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. This medication must not be stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience neuroleptic malignant syndrome, characterized by fever, muscle rigidity, and altered consciousness or seizures.
Some common side effects of this medicine include nausea, insomnia(difficulty sleeping), anxiety, fatigue, akathisia (restlessness and inability to stay still), and depression. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.
Ticstop Tablet works by depleting the stores of certain chemical messengers (such as dopamine, serotonin, norepinephrine, and histamine) in the brain that helps in controlling body movements.
Tetrabenazine acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2. As a result of this inhibition, monoamine degradation in the neuron is augmented, leading to depletion of the monoamines, particularly dopamine.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ticstop
Nausea
Insomnia (difficulty in sleeping)
Anxiety
Fatigue
Sleepiness
Akathisia (inability to stay still)
Depression
Tetrabenazine should not be prescribed for patients who are actively suicidal, for patients with untreated or inadequately treated depression, or for patients with hepatic impairment. It should not be used in conjunction with monoamine oxidase inhibitors or reserpine.
Ticstop Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Ticstop Tablet may cause excessive drowsiness with alcohol.
Ticstop Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Tetrabenazine is indicated for hyperkinetic motor disorders with Huntington's chorea. Dosage and administration are individual in each patient and therefore only a guide is given. An initial starting dose of 12.5 mg/day one to three times a day is recommended.
The metabolism of Tetrabenazine can be decreased when combined with Azelastine. The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Tetrabenazine. The risk or severity of QTc prolongation can be increased when Tetrabenazine is combined with Bedaquiline.
Do not chew, crush or break it. Ticstop Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Ticstop Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Ticstop Tablet to help control movement disorders such as in Huntington’s disease.
Be cautious while driving or doing anything that requires concentration as Ticstop Tablet can cause dizziness and sleepiness.
Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as the neuroleptic malignant syndrome.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking Ticstop Tablet without talking to your doctor first as it may cause worsening of symptoms.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ticstop Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can Ticstop Tablet be crushed?
No, Ticstop Tablet should not be crushed, cut, or chewed. It needs to be swallowed as a whole. But if you cannot swallow the whole tablet, tell your doctor who will probably prescribe you another medicine.
Q. Is Ticstop Tablet an antipsychotic?
Ticstop Tablet is not an antipsychotic. It belongs to the vesicular monoamine transporter 2 (VMAT2) inhibitor class of medicines. It works by changing the activity of some natural substances in the brain that affect muscles and nerves.
Q. What is the most important information that I should know about Ticstop Tablet?
Ticstop Tablet may increase the risk of depression or suicidal thoughts in patients with Huntington’s disease. Huntington’s disease is an inherited disease that causes the progressive breakdown of nerve cells in the brain. Therefore, you should not take Ticstop Tablet if you have Huntington’s disease along with depression.
Q. What should I avoid while taking Ticstop Tablet?
Sleepiness is a common side effect of Ticstop Tablet. Therefore, you should avoid driving or operating heavy machinery if you feel sleepy while taking Ticstop Tablet.
