Manufacturer: Tablets India Limited
Salt Composition : Neostigmine(15mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Tilstigmin Tablet works by reducing and improving muscle weakness. It may be taken with or without food, preferably at the same time each day. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment. You should never stop this medicine suddenly without talking to your doctor.
Some common side effects of using this medication are nausea, vomiting, abdominal cramps, increased production of saliva, and diarrhea. It usually does not cause dizziness and sleepiness. But, if you feel ill, avoid doing any such work that requires focus and attention, such as driving or operating any machinery.
Before taking Tilstigmin Tablet, it is better to inform your doctor if you are suffering from any kidney problems, Parkinson's disease, asthma, or stomach disorders. Your blood pressure may decrease after taking this medicine, so it is better to monitor it and consult your doctor if it bothers you. This medicine may cause diarrhea, so drink plenty of fluids to keep yourself hydrated while taking this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding, before taking this medicine.
Tilstigmin Tablet is a reversible cholinesterase inhibitor. When taken by mouth it increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.
Neostigmine is metabolized by microsomal enzymes in the liver and the observed elimination half-life reported is between 24 and 113 minutes. Metabolism Neostigmine is metabolized by microsomal enzymes in the liver.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tilstigmin
Nausea
Vomiting
Abdominal cramp
Diarrhea
Increased saliva production
Absolute contraindications of neostigmine include hypersensitivity to neostigmine and peritonitis or mechanical obstruction of the intestinal or urinary tract.
Tilstigmin Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Tilstigmin Tablet may cause excessive drowsiness with alcohol.
Tilstigmin Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Neostigmine, sold under the brand name Bloxiverz, among others, is a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage. It is also used in anaesthesia to end the effects of non-depolarising neuromuscular blocking medication.
Drug-Drug Interaction: NEOSTIGMINE may interact with anaesthetics (halothane, cyclopropane), muscle relaxants (succinylcholine, suxamethonium), antibiotics (neomycin, streptomycin), muscle weakness treating drugs (amifampridine), antidepressants (bupropion), and dementia treating drugs (donepezil).
Drug-Food Interaction: Avoid or limit alcohol intake to prevent disease worsening and unwanted side effects.
Drug-Disease Interaction: Let your doctor know if you have asthma, bradycardia (slow heart rate), bronchospasm, fits, hyperthyroidism, stomach ulcer, coronary artery disease, urination problems, Parkinson's disease, or irritability of vagus nerve before starting NEOSTIGMINE.
Drug-Drug Interactions Checker List:
HALOTHANE
CYCLOPROPANE
SUCCINYLCHOLINE
SUXAMETHONIUM
NEOMYCIN
STREPTOMYCIN
AMIFAMPRIDINE
BUPROPION
DONEPEZIL
Do not chew, crush or break it. Tilstigmin Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Tilstigmin Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Tilstigmin Tablet for treatment of myasthenia gravis.
It may also be used to treat inactivity of the muscle in the intestines (paralytic ileus) and difficulty in passing urine (urinary retention) after an operation.
Take it as per the dose and duration advised by your doctor. Overdosing can result in extreme muscle weakness.
Do not drink alcohol while taking this medicine as it may worsen the side effects.
Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tilstigmin Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Does Tilstigmin Tablet treat myasthenia gravis? How long do I need to take it?
Tilstigmin Tablet relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Tilstigmin Tablet will depend on your condition. Do not stop taking Tilstigmin Tablet until and unless advised by your doctor, even if you start feeling better.
Q. How long does Tilstigmin Tablet take to start working?
Tilstigmin Tablet takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.
Q. Is Tilstigmin Tablet a steroid?
No, Tilstigmin Tablet is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Tilstigmin Tablet work by preventing the breakdown of a chemical called acetylcholine.
Q. Does it cause weight gain?
No, Tilstigmin Tablet does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.
