Tiomate 6 mcg / 9 mcg Transhaler

Manufacturer: Lupin Ltd

Salt Composition : Formoterol(6mcg), Tiotropium(9mcg)


Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your COPD may get worse. To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.

The most common side effects are nausea, diarrhea, dryness in mouth, vomiting, dizziness, nasopharyngitis (inflammation of the throat and nasal passages), and insomnia. If you get there, don’t stop taking it but do talk to your doctor. You can prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them.


Basic Information

Mechanism Of Action

Tiomate Transcaps is a combination of two medicines: Formoterol and Tiotropium. Formoterol is a bronchodilator while Tiotropium is an anticholinergic. They work by relaxing the muscles in the airways and widen the airways. Together, they make breathing easier.


Pharmacokinets

Formoterol, a long-acting beta 2-selective adrenoceptor agonist, produces dose-proportional bronchodilation in patients with obstructive airways disease with a reversible component. A significant effect occurs within minutes of inhalation of a therapeutic formoterol dose and persists for approximately 12 hours.Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tiomate

Nausea

Diarrhea

Dryness in mouth

Vomiting

Dizziness

Nasopharyngitis (inflammation of the throat and nasal passages)

Insomnia (difficulty in sleeping)

Contra Indications

If you are suffering from any of the following diseases, you should not take Formoterol + Tiotropium unless your doctor advises you to do so -

Asthma

Diabetes

Epilepsy

Heart Disease

Kidney Disease

Potassium Deficiency

Glaucoma

Angioedema

Liver Disease

Kidney Disease

Pregnancy Related Information

Tiomate Transcaps may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Tiomate Transcaps.


Breast Feeding Related Information

Tiomate Transcaps is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Monitor the baby for dry mouth, constipation, and urinary problems.

Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

FORMOTEROL+TIOTROPIUM is a respiratory medication primarily used to treat and prevent asthma and chronic obstructive pulmonary diseases (COPD) like bronchitis (inflammation of the lining of your bronchial tubes) and emphysema (shortness of breath).

Interactions

FORMOTEROL+TIOTROPIUM may interact with fluid retention drugs (furosemide), corticosteroids (budesonide, mometasone, beclomethasone), bronchodilators (vilanterol, salmeterol, albuterol), respiratory drugs (ipratropium), drugs treating irregular heartbeat (sotalol), and blood pressure medicines (metoprolol).

Typical Dosage

Check the label for directions before use. Place the capsule at the base of transhaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the transhaler repeat the process.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Tiomate Transcaps, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

You have been prescribed Tiomate Transcaps for the treatment of chronic obstructive pulmonary disease (COPD).

If at any time your breathing gets worse, please contact your doctor or nurse for advice straightaway.

Do not smoke. Smoking causes irritation and damage to the lungs and will make your condition worse.

If you have diabetes you may need to check your blood glucose more frequently, as Tiomate Transcaps can affect the levels of sugar in your blood. Your doctor will advise you about this.

Do not discontinue use without consulting your doctor, even if you feel better.

If you are overweight, it is advisable to lose weight. This is because being overweight means that you have to work much harder to breathe in to inflate your lungs.

How To Use

Trancaps must not be swallowed. Check the label for directions before use. Place the capsule at the base of transhaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the transhaler repeat the process.