Manufacturer: Cipla Ltd
Salt Composition : Tobramycin(300mg)
Tobamist Respules is only meant for inhalation using a nebulizer. The solution should not be injected or swallowed. It works by stopping the growth of bacteria. This helps to improve your symptoms and resolve the underlying infection. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.
Common side effets of this medicine include increased may cause cough, pharyngitis, change in taste, or voice change as side effects in some patients. These are temporary and usually resolve with time. Regular rinsing of the mouth with warm saline water and the use of lozenges may help you to overcome the side effects. Consult your doctor if any of the side effects persist or if your condition does not improve.
Your doctor may advise you periodic blood counts and kidney function tests for monitoring. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding before using this medicine.
Tobamist Respules is an antibiotic. It stops bacterial growth in the airways by preventing synthesis of essential proteins required by bacteria to carry out vital functions. This treats infection in the airways.
Tobramycin is not appreciably metabolized. Tobramycin is primarily excreted unchanged in the urine. Tobramycin has an apparent serum terminal half-life of ~3 hours following a single 112 mg inhaled dose in cystic fibrosis patients.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tobamist
Taste change
Voice change
Rash
Coughing up blood
Breathlessness
Sore throat
Cough
Increased sputum production
Lung disorder
A hypersensitivity to any aminoglycoside is a contraindication to the use of tobramycin. A history of hypersensitivity or serious toxic reactions to aminoglycosides may also contraindicate the use of any other aminoglycoside because of the known cross-sensitivity of patients to drugs in this class.
Tobamist Respules is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Tobamist Respules does not cause any harmful side effects.
Tobamist Respules is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
indicated in adult and pediatric patients for the treatment of serious bacterial infections, including septicemia (caused by P. aeruginosa, Escherichia coli, and Klebsiella spp.), lower respiratory tract infections (caused by P. aeruginosa, Klebsiella spp., Enterobacter spp., Serratia spp., E.
Some products that may interact with this drug include: botulinum toxin, neostigmine, pyridostigmine. Other medications that may affect hearing or cause kidney damage may increase the risk of hearing loss or kidney problems if taken with tobramycin.
Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Tobamist Respules, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Tobamist Respules is used for long-term management of chronic lung infections in patients with cystic fibrosis.
This medicine is for inhalation using a nebuliser only. The solution should not be injected or swallowed.
Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
Inform your doctor if you experience any hearing loss, sensation of ringing in the ears, or dizziness and unsteadiness.
Your doctor will regularly monitor your kidney function while taking Tobamist Respules to detect any toxicity.
Can I stop taking Tobamist Respules when I feel better?
Do not skip any doses and finish the full course of treatment even if you feel better.
Tobamist Respules may cause damage to cornea on long-term use.
Apply pressure on the corner of the eye (close to the nose) for about 1 minute immediately after instilling the drop.
Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
Stinging sensation may occur for 1-2 mins. Notify your doctor if it persists for longer.
Make sure to use it within 4 weeks of opening the bottle.
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.
Q. How do you give Tobamist Respules?
Tobamist Respules is given via a nebulizer for inhalation purpose. Your healthcare provider will teach you the method of taking it. Take it exactly as prescribed by your doctor. Use 2 single containers per day for 28 days. Inhale the contents of 1 container in the morning and one in the evening. After taking it for 28 days, stop for 28 days and then again take the medicine for 28 days. Maintain this 28 days on and 28 days off cycle. Try to keep the 2 doses 12 hours apart. Do not take your dose less than 6 hours apart.
Q. Should Tobamist Respules be refrigerated?
Yes, Tobamist Respules inhalation solution should be refrigerated at 2- 8°C/36-46°F. Upon removal from refrigeration or if refrigerator is unavailable, the solution pouches (opened/unopened) should be stored at room temperature (up to 25°C/77°F) for up to 28 days. It should not be exposed to intense light. Not storing it in the refrigerator may darken the medicine. However, color change does not indicate change in quality.
Q. Is Tobamist Respules bad for kidneys?
Yes, Tobamist Respules belongs to aminoglycoside class of antibiotic medicine, which may affect the kidney function. However, there is no firm evidence to suggest so. If your kidney function is already impaired, then you should be careful while using Tobamist Respules. Your doctor will get your kidney function tested before starting Tobamist Respules and at regular intervals during treatment. Tell your doctor if you experience decreased urination, unusual tiredness or weakness or swelling of the face, arms, hands, feet, ankles, or lower legs.
Q. What is antibiotic resistance? Does this occur with Tobamist Respules?
Sometimes the bacteria gets modified in your body and the medicine no longer works. This is called drug resistance. Resistance can occur with Tobamist Respules if it is used inappropriately, for example if you do not adhere to the dose and duration of therapy. It may also occur if you use it for viral and fungal infections instead of bacterial infections. Therefore, it is important that you continue taking Tobamist Respules for the duration advised by your doctor even if you start feeling better.
