Manufacturer: Janssen Pharmaceuticals
Salt Composition : Topiramate(100mg)
Topamac 100mg Tablet may be taken with or without food, preferably at the same time, each day. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. Stopping the medication suddenly without talking to your doctor may cause an increased frequency of seizures. Your doctor may advise regular monitoring of serum bicarbonate levels while you are taking this medicine.
Topamac 100mg Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence.
The pharmacokinetics of topiramate are linear with dose proportional increases in plasma concentration over the dose range studied (200 to 800 mg/day). The mean plasma elimination half-life is 21 hours after single or multiple doses. Steady state is thus reached in about 4 days in patients with normal renal function.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Topamac
Abdominal pain
Diarrhea
Dizziness
Fatigue
Fever
Loss of appetite
Memory impairment
Nausea
Nervousness
Numbness
Psychomotor impairment
Sleepiness
Speech disorder
Taste change
Upper respiratory tract infection
Visual impairment
Weight loss
If you are suffering from any of the following diseases, you should not take Topiramate unless your doctor advises you to do so -
Depression
Suicidal Tendency
COPD (Chronic Obstructive Pulmonary Disease)
Liver Disease
Topamac 100mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Topamac 100mg Tablet.
Topamac 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Topiramate is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
bone marrow depression/blood dyscrasias.
oligohidrosis/hyperthermia.
severe liver disease.
suicidal tendency.
renal dysfunction.
metabolic acidosis.
angle closure glaucoma.
hemodialysis.
Do not chew, crush or break it. Topamac 100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Topamac 100mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
Practice yoga every day.
Get enough sleep at nighttime.
Limit the use of screen time such as mobile/laptop.
Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Topamac 100mg Tablet. This can reduce the risk of kidney stones.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topamac 100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. For how long do I need to take Topamac 100mg Tablet?
The dose and duration of this medicine will depend on your doctor’s advice. Topamac 100mg Tablet does not cure your condition (seizures/migraine) but prevents them from occurring. So, you may have to keep taking it for months or years depending on improvement in your symptoms and side effects that may occur.
Q. Is Topamac 100mg Tablet good for anxiety?
Topamac 100mg Tablet is not indicated for the treatment of anxiety. Please consult your doctor before taking the medicine.
Q. What are the serious side effects of Topamac 100mg Tablet?
Serious side effects of Topamac 100mg Tablet are rare. The serious effects of Topamac 100mg Tablet may include glaucoma (difficulty in seeing, eye pain, and blurred vision), kidney stones (sharp pain in your sides or lower back), and metabolic acidosis (tiredness, loss of appetite, irregular and faint heartbeat). Other serious side effects of Topamac 100mg Tablet could be suicidal thoughts and insufficient sweating (some children taking Topamac 100mg Tablet may not sweat enough in hot weather, causing their body temperatures to rise).
Q. I am taking valproic acid for fits. Will Topamac 100mg Tablet interfere with the working of valproic acid? Can this combination be taken?
Topamac 100mg Tablet does not interfere with the working of valproic acid, but it increases the risk of getting excess levels of ammonia in the blood (hyperammonemia). Increased levels of ammonia in the blood can be dangerous and may cause difficulty in thinking, remembering information, or solving problems. It may also decrease your alertness and make you feel very sleepy with low energy. Immediately inform your doctor if you notice these symptoms. It is important to know that, in rare cases, Topamac 100mg Tablet alone can cause hyperammonemia.
Q. Can Topamac 100mg Tablet be used in children?
Yes, Topamac 100mg Tablet is used for seizures in children more than 2 years of age. However, because of the lack of any reports, this medicine is not recommended to be used in children for migraines.
Q. Since I have started using Topamac 100mg Tablet people are saying that I have lost weight. Is it because of Topamac 100mg Tablet or something else for which I should get investigated?
It could be due to Topamac 100mg Tablet because Topamac 100mg Tablet commonly causes weight loss probably due to a decrease in appetite. If you still have any doubts, talk to your doctor who will advise you appropriately.
