Manufacturer: Franco-Indian Pharmaceuticals Pvt Ltd
Salt Composition : Clotrimazole(2% w/v), Clobetasol(0.05% w/v), Neomycin(3500u/ml)
Topifort-NX Topical Suspension is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after applying the medicine. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure the better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.
This is usually a safe medicine, however, it may cause dryness, peeling, redness, and burning sensation at the application site. These side effects are usually mild and self-limiting. Most of these side effects can be prevented by using a skin moisturizer and drinking plenty of water. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.).
Before using this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should use this medicine with proper consultation and caution. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. During the course of the treatment, do not touch, prick or scratch the infected skin areas as this may worsen or spread the acne. Avoid unnecessary sun exposure and use sunscreen before stepping out in the sun. It is also advised, not to receive any cosmetic procedures without asking your doctor.
Clobetasol is a steroid that acts by blocking the synthesis of natural substances, i.e. prostaglandins which is responsible for itching, swelling and redness.
Clotrimazole works by inhibiting the formation of a fungal cell wall component which leads to altered permeability and growth of fungus causing infection.
Neomycin is an antibiotic agent which is widely used for treating various bacterial infections of the skin. It works by inhibiting the growth and multiplication of bacteria causing infection.
Collectively all these medicines work more effectively by reducing the infection and inflammation of the skin.
Clotrimazole acts primarily by damaging the permeability barrier in the cell membrane of fungi. Clotrimazole causes inhibition of ergosterol biosynthesis, an essential constituent of fungal cell membranes.Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.Neomycin is bactericidal in action. Similar to other aminoglycosides, it inhibits bacterial protein synthesis through irreversible binding to the 30 S ribosomal subunit of susceptible bacteria.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Topifort-NX
Application site reactions (burning, irritation, itching and redness)
Hypersensitivity to Topifort Nx Topical Suspension is a contraindication. In addition, Topifort Nx Topical Suspension should not be used if you have the following conditions:
First trimester of pregnancy
Hypersensitivity
Hypersensitivity to imidazole
Lactation
Pregnancy
Renal impairment
Usage in pediatric patients under 12 years of age is not recommended
Topifort-NX Topical Suspension may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Topifort-NX Topical Suspension is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Clotrimazole+Clobetasol+Neomycin is used in the treatment of skin infections.Clotrimazole is an antifungal which stops the growth of fungi by preventing them from forming their own protective covering. Clobetasol is a steroid medicine. It blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Neomycin is an antibiotic. It stops bacterial growth by preventing the synthesis of essential proteins required by the bacteria to carry out vital functions.
If you use other drugs or over the counter products at the same time, the effects of Topifort Nx Topical Suspension may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Topifort Nx Topical Suspension may interact with the following drugs and products:
Acarbose
Aminoglycosides
Amphotericin
Atracurium
Capreomycin
Cephalosporins
Cyanocobalamin
Cyclosporin
Digoxin
Doxacurium
Check the label for directions before use.
Store below 30°C
If you miss a dose of Topifort-NX Topical Suspension, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Topifort-NX Topical Suspension must be applied as a thin layer on the affected area as prescribed by your doctor.
Do not use this medicine more often or for longer than advised by your doctor.
Before each application, wash the affected area with soap and water and dry well.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use.
Q. Can I stop taking Topifort-NX Topical Suspension when my symptoms are relieved?
No, do not stop using Topifort-NX Topical Suspension and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.
Q. What precautions should I take while using Topifort-NX Topical Suspension?
Topifort-NX Topical Suspension should not be used on the face and any contact with the eyes should be avoided. Do not apply a bandage or dressing on the area being treated, as this will increase absorption of the medicine and increase the risk of side effects. This medicine should only be used for the condition it is prescribed for. Do not use it for any other condition without consulting your doctor. Do not give it to other people even if their condition appears to be the same.
Q. How to use Topifort-NX Topical Suspension?
Topifort-NX Topical Suspension should be used as advised by the doctor or as per the instructions on the label of the medicine. Apply a thin layer of Topifort-NX Topical Suspension to cover the affected areas. The dose would depend on the condition for which it is prescribed. Wash your hands after using Topifort-NX Topical Suspension unless it is used for treating infection of the hands. Avoid contact with the eyes.
Q. What would happen if I use a higher than the recommended dose of Topifort-NX Topical Suspension and for long periods?
The dosage and duration of using Topifort-NX Topical Suspension should be strictly according to the doctor’s advice. This medicine contains clobetasol which when used in higher doses and for longer periods can get absorbed in the blood and cause adrenal suppression and Cushing's syndrome. It can cause weight gain, high blood pressure and rounding of the face. Its application can lead to a change in color of skin at the site of application. Veins beneath the skin become visible due to the thinning and weakening of the skin. There could be an increased hair growth. If you experience an increased severity of your symptoms, please consult your doctor for re-evaluation.
Q. What are the instructions for the storage and disposal of Topifort-NX Topical Suspension?
Keep this medicine in the packet or the container it came in. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
