Tosiban 37.5mg Injection (5ml)

Manufacturer: Zuventus Healthcare Ltd

Salt Composition : Atosiban(37.5mg)


Tosiban 37.5mg Injection is generally administered by a doctor or a nurse in a clinical setting. Do self-administered this medicine at home. The dose and how often you get the injection depends on what you are taking it for and the severity of the symptoms. Your doctor will decide the exact dose, hence follow your doctor's advice. It is not given for more than 3 treatments, make sure do not exceed the treatment duration.


The most common side effects of this medicine include injection site reaction, headache, nausea, vomiting, increased sugar level, and low blood pressure (dizziness). If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. To overcome dizziness rise slowly while from sitting or lying position.


Before taking this medicine, tell your doctor if you have ever had kidney or liver disease, or if you are pregnant more than 24 weeks or you are pregnant with two babies. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Your doctor may check you for contraction and baby heart rate during treatment.


Basic Information

Mechanism Of Action

Tosiban 37.5mg Injection works by blocking the action of a natural hormone called Oxytocin. It is hormone which causes the uterus (womb) to contract. Blocking the action of Oxytocin helps to delay the premature birth of the baby.


Pharmacokinets

Atosiban is given initially by intravenous bolus injection followed by an infusion; it has a short half-life (0.2–1.7 h).

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tosiban

Injection site reaction

Headache

Nausea

Increased glucose level in blood

Decreased blood pressure

Dizziness

Hot flashes

Slow heart rate

Vomiting

Contra Indications

Atosiban must not be used in the following conditions: - Gestational age below 24 or over 33 completed weeks - Premature rupture of the membranes >30 weeks of gestation - Abnormal foetal heart rate - Antepartum uterine haemorrhage requiring immediate delivery - Eclampsia and severe pre-eclampsia requiring delivery -

Pregnancy Related Information

Tosiban 37.5mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Tosiban 37.5mg Injection. Please consult your doctor.


Breast Feeding Related Information

Tosiban 37.5mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

regular uterine contractions of at least 30 s duration at a rate of at least 4 per 30 min.

a cervical dilation of 1-3cm (0-3cm for nulliparas) and effacement of at least 50%

a gestational age of 24-33 weeks.

Interactions

Drug-Drug Interactions: ATOSIBAN may interact with a medicine used to treat high blood pressure and irregular heartbeat (e.g. acebutolol, sotalol, quinidine), antiplatelet drugs (e.g. anagrelide), medications to treat or prevent HIV/AIDS (e.g. saquinavir), antipsychotic drugs (e.g. thioridazine, ziprasidone) and anti- ...


Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Tosiban 37.5mg Injection helps delay premature birth of your baby.

It is given as an injection into a vein followed by infusions (drip).

During treatment with Tosiban 37.5mg Injection, your contractions and your unborn baby’s heart rate may be monitored.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What is Tosiban 37.5mg Injection and what is it used for?

Tosiban 37.5mg Injection is an injectable preparation, which contains a medicine called Atosiban. It is used in the treatment of premature labor, a condition when uterus starts contracting for birth too early than usual. It is used in pregnant adult women, from week 24 to week 33 of the pregnancy.

Q. How and in what dose can it be used?

It is given as an injection, only at the hospital or clinic by the medical healthcare professional. The dose and the length of the treatment is decided by the doctor, depending on the contraction pattern or the current medical situation of the patient.

Q. What may be the possible side effects associated with it?

It may cause headache, nausea, vomiting, dizziness, hot flushes, low blood pressure and fast heart beat. However, these conditions are manageable in hospital settings.