Manufacturer: Sanofi India Ltd
Salt Composition : Insulin Glargine(300u/ml)
Toujeo 300 U/mL Solostar can be prescribed alone or along with fast-acting insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. You should use this medicine regularly as per the dose advised to get the maximum benefit. If you stop taking it, your blood sugar levels may rise very high which may put you at risk of serious complications. It is only a part of the treatment program that should also include a healthy diet, regular exercise and weight reduction as advised by your doctor.
The most common side effect of this medicine is low blood sugar levels (hypoglycemia). To prevent this, it is important to inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other common side effects include peripheral edema, lipodystrophy, allergic reactions, injection site reactions, irching, rashes, and weight gain.
Do not use this medicine when you have low blood sugar levels. Before starting the treatment, inform your doctor if you have ever had kidney, liver or heart problems. Pregnant or breastfeeding women should consult their doctor before using it.
Toujeo 300 U/mL Solostar is a long-acting insulin that provides consistent, all-day sugar control. It works like your body's natural insulin. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.
The pharmacokinetic profiles for single 0.4, 0.6, and 0.9 U/kg doses of Toujeo in 24 patients with type 1 diabetes mellitus was evaluated in a euglycemic clamp study. The median time to maximum serum insulin concentration was 12 (8–14), 12 (12–18), and 16 (12–20) hours, respectively.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Toujeo
Hypoglycemia (low blood glucose level)
Peripheral edema
Lipodystrophy (skin thickening or pits at the injection site)
Allergic reaction
Injection site reactions (pain, swelling, redness)
Itching
Rash
Weight gain
You should not use insulin glargine if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar) or diabetic ketoacidosis (call your doctor for treatment). Different brands of insulin glargine are specifically approved for different age groups and different diabetes types.
Toujeo 300 U/mL Solostar is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is unsafe to consume alcohol with Toujeo 300 U/mL Solostar.
Toujeo 300 U/mL Solostar is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Insulin glargine is a synthetic version of human insulin that is FDA approved to treat adults and children with type 1 diabetes and adults with type 2 diabetes to improve and maintain glycemic control. Insulin glargine is a long-acting insulin injected once daily and provided a basal insulin level throughout the day.
Drug-Drug Interactions: INSULIN GLARGINE may have an interaction with all other antidiabetic pills (sitagliptin), blood sugar enhancers (diazoxide), blood pressure-lowering pills (metoprolol, clonidine), antidepressants (lithium, fluoxetine), pain killers (aspirin, pentoxifylline, propoxyphene), anti TB drug (isoniazid), growth hormone (somatropin), thyroid hormone-related drugs (levothyroxine), antipsychotic medicines (phenothiazine, clozapine, olanzapine), anti-cholesterol drugs (fenofibrate), anti-asthmatic (epinephrine, salbutamol, terbutaline), female hormones like oestrogens and progestogens.
Drug-Food Interactions: INSULIN GLARGINE may interact with an ayurvedic, homoeopathy, Unani, herbal supplements or OTC items. Tell your doctor if you are using these products. Avoid drinking alcoholic beverages with INSULIN GLARGINE as it may raise or lower your blood sugar level.
Drug-Disease Interactions: INSULIN GLARGINE should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).
Drug-Drug Interactions Checker List:
ASPIRIN
SITAGLIPTIN
PREGABALIN
METOPROLOL
LEVOTHYROXINE SODIUM
CLONIDINE
LITHIUM
FLUOXETINE
RIFAMPICIN+ISONIAZID
CLOZAPINE
OLANZAPINE
FENOFIBRATE
EPINEPHRINE
SALBUTAMOL
ESTROGEN
PROGESTERONE
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Toujeo 300 U/mL Solostar, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Toujeo 300 U/mL Solostar is injected under the skin. It needs to be injected once daily, at the same time every day.
Injection below the skin of the abdomen results in faster absorption than other injection sites.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
Hypoglycemia (low blood sugar level) is a common side effect. Hence, regular monitoring of blood sugar levels is required while taking this medicine.
Always carry some high sugar food such as sugar candy or glucose candy, fruit juice and glucose/glucon-D with you so that you can take it when you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
Opened vials/cartridge stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Do not use if the preparation is no longer clear and colorless, or if it contains particles.
Your doctor or nurse will guide you how to use this medicine.
Q. What kind of insulin is Toujeo 300 U/mL Solostar?
Toujeo 300 U/mL Solostar is a man-made insulin, which is very similar to human insulin. It has a long and steady (constant) effect on the blood sugar levels and the action lasts for an entire day. This makes it suitable to be used once daily. It is used to treat type 2 diabetes mellitus in adults and type 1 diabetes mellitus in adults and children.
Q. How is Toujeo 300 U/mL Solostar administered?
Toujeo 300 U/mL Solostar is injected just below the skin (subcutaneously). Your doctor will train you on the correct method and the areas (abdomen or stomach, thighs, arms, hips or buttocks) where you should inject it. It is advised that the site of injection should be changed within the chosen area of skin, for every dose. For example, if you have been advised to inject it into the skin of your stomach, avoid puncturing the same point on your stomach every day. Rather, inject the needle at a site that is slightly away, say around 1cm, from the previous injection. You can also consider switching sides while injecting, like choosing the right side on one day and the left side on the next day. This way, you can reduce the complications associated with repeated injections in the same site such as thickening of the fat tissue below the skin known as lipodystrophy, irritation, pain etc. After one to two weeks, you should move to another area of your body (eg. from the stomach to the arms or thighs) as advised by your doctor. Consult your doctor if you face any problems while injecting Toujeo 300 U/mL Solostar.
Q. Can I take Toujeo 300 U/mL Solostar twice a day?
Toujeo 300 U/mL Solostar is long-acting and is usually prescribed to be taken once a day. It can be taken at any time of the day, but try to take it at the same time each day.
Q. What will happen if I accidentally inject more than the prescribed dose of Toujeo 300 U/mL Solostar?
If you have accidentally taken more than the prescribed dose of Toujeo 300 U/mL Solostar, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, fast heartbeat) can usually be corrected with the help of sugary foods such as sugary candy, fruit juice, and glucose/glucon-D. However, it is important to consult your doctor to decide the further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening and the patient should be rushed to an emergency.
