Manufacturer: Boehringer Ingelheim
Salt Composition : Metformin(1000mg), Linagliptin(2.5mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Trajenta Duo 2.5mg/1000mg Tablet can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking this medicine with meals helps to reduce the chances of developing an upset stomach.
Trajenta Duo 2.5 mg/ 1000 mg Tablet is a combination of Metformin and Linagliptin. Metformin works by improving the body's response to insulin (a chemical substance that helps regulate blood sugar levels) and decreasing sugar production in the liver.
Metformin is rapidly distributed following absorption and does not bind to plasma proteins. No metabolites or conjugates of metformin have been identified. The absence of liver metabolism clearly differentiates the pharmacokinetics of metformin from that of other biguanides, such as phenformin.
The pharmacokinetics of linagliptin has been extensively characterised in healthy subjects and patients with type 2 diabetes. After oral administration of a 5 mg dose to healthy volunteers or patients, linagliptin was rapidly absorbed, with peak plasma concentrations (median Tmax) occurring 1.5 hours post-dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trajenta Duo
Hypoglycemia (low blood glucose level)
Nausea
Diarrhea
Vomiting
Flatulence
Weight gain
Renal dysfunction.
Congestive cardiac failure needing drug treatment.
Hypersensitivity to metformin.
Acute or chronic metabolic acidosis.
Impaired hepatic function.
Contraindications / Precautions. Linagliptin is contraindicated in patients with a history of hypersensitivity to linagliptin, such as anaphylaxis, urticaria, angioedema, exfoliative dermatitis or other serious allergic skin condition (serious rash), or bronchial hypersensitivity.
Trajenta Duo 2.5mg/1000mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Trajenta Duo 2.5mg/1000mg Tablet.
Trajenta Duo 2.5mg/1000mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Trajenta Duo 2.5mg/1000mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a heart attack or stroke.
The use of Trajenta Duo 2.5mg/1000mg Tablet may cause some common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. It can also lead to a serious but rare side effect known as lactic acidosis.
Do not chew, crush or break it. Trajenta Duo 2.5mg/1000mg Tablet
Store below 30°C
If you miss a dose of Trajenta Duo 2.5mg/1000mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
Trajenta Duo 2.5mg/1000mg Tablet should be taken with food to lower the chances of having an upset stomach.
Take it in addition to regular exercise and a healthy diet to lower the levels of blood sugar.
Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have any surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, or stomach pain as Trajenta Duo 2.5mg/1000mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trajenta Duo 2.5mg/1000mg Tablet is to be taken with food.
Q. Can the use of Trajenta Duo 2.5mg/1000mg Tablet cause lactic acidosis?
Yes, the use of Trajenta Duo 2.5mg/1000mg Tablet can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Trajenta Duo 2.5mg/1000mg Tablet and immediately consult your doctor.
Q. What are the possible side effects of Trajenta Duo 2.5mg/1000mg Tablet?
The use of Trajenta Duo 2.5mg/1000mg Tablet may cause some common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. It can also lead to a serious but rare side effect known as lactic acidosis. Additionally, its long-term use can also lead to vitamin B12 deficiency.
Q. Are there any specific conditions in which Trajenta Duo 2.5mg/1000mg Tablet should not be taken?
The use of Trajenta Duo 2.5mg/1000mg Tablet should be avoided in patients with known allergy to any of the components of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis. Therefore, consult your doctor before using Trajenta Duo 2.5mg/1000mg Tablet.
Q. Is it safe to take alcohol while I am also taking Trajenta Duo 2.5mg/1000mg Tablet?
No, it is not safe to take Trajenta Duo 2.5mg/1000mg Tablet along with alcohol. Doing so can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition or kidney dysfunction. However, if you are not sure, consult your doctor.
