Manufacturer: Ind Swift Laboratories Ltd
Salt Composition : Tranexamic Acid(500mg)
Vial of 5ml Injection
(Inclusive of all taxes)
Tranee 500mg Injection is used to treat bleeding. It helps to prevent or reduce bleeding in conditions like tooth removal, heavy periods, dysfunctional uterine bleeding, nosebleed, and in any oral, prostate, or bladder surgery.
Tranee 500mg Injection is an anti-fibrinolytic. It works by preventing the breakdown of clots which leads to the stoppage of bleeding. This injection must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergy to this injection.
The most common side effects of this medicine include injection site reactions, tiredness, musculoskeletal pain, and nasal congestion. Inform your doctor if you have undergone any cardiac surgery or you are suffering from any kidney disease. This injection is safe to use in pregnant or breastfeeding mothers. It is also safe to use in patients suffering from liver diseases.
Tranexamic acid is a synthetic derivative of the amino acid lysine and binds the 5 lysine binding sites on plasminogen. This inhibits plasmin formation and displaces plasminogen from the fibrin surface. It may also directly inhibit plasmin and partially inhibit fibrinogenolysis at higher concentrations
Tranexamic acid 1 g was given intravenously to three healthy volunteers. Plasma concentrations decayed in three monoexponential phases. Most elimination took place during the first eight hours, giving an apparent elimination half-life of approximately two hours. Plasma clearance ranged between 110-116 ml/min.
Musculoskeletal (bone, muscle or joint) pain
Joint pain
Headache
Back pain
Vomiting
Nausea
Abdominal pain
Fatigue
Diarrhea
Hypotension (low blood pressure)
Sinus disorder
Nasal discomfort
Muscle cramp
Migraine
Anemia (low number of red blood cells)
Allergic dermatitis
Lightheadedness
Thromboembolism
increased risk of blood clotting.
fluid accumulation in the brain.
a clot in the small veins that carry blood to or from the retina of the eye.
a heart attack.
acute blood clot in a blood vessel supplying the lungs.
heart valve disease.
Tranee 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Tranee 500mg Injection may cause excessive drowsiness with alcohol.
Tranee 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Tranexamic acid (sometimes shortened to txa) is a medicine that controls bleeding. It helps your blood to clot and is used for nosebleeds and heavy periods. If you're having a tooth taken out, using tranexamic acid mouthwash can help stop bleeding
Some products that may interact with this drug include: "blood thinners" (anticoagulants such as warfarin, heparin), drugs that prevent bleeding (including factor IX complex, anti-inhibitor coagulant concentrates), estrogens, hormonal birth control (such as pills, patch, ring), tibolone, tretinoin.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Tranee 500mg Injection, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines
Tranee 500mg Injection helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
It is given as a slow injection into a vein.
Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
Your doctor may monitor your vision regularly while you are taking this medicine
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can Tranee 500mg Injection be given or injected into muscles?
No, Tranee 500mg Injection should not be administered by injection into the muscles. It should be given strictly through slow injection into the veins to prevent side effects.
Q. Is Tranee 500mg Injection dangerous?
Every medicine has its own side effects and these side effects are unlikely to happen if taken as directed. Usually, the benefits of the medicine are greater than the risk of side effects. Tranee 500mg Injection can rarely cause serious side-effects which can be dangerous, like anaphylaxis (red and lumpy skin rash, difficulty breathing, swelling of face, mouth, lips or eyelids), clot in another part of the body or eye problems. Do consult your doctor before you start this medication and follow the instructions strictly as given.
Q. Can Tranee 500mg Injection cause DVT?
Yes, Tranee 500mg Injection promotes blood clotting, thereby preventing blood loss. However, in rare cases, this can lead to a chance of developing a clot in the deep leg veins, a condition known as deep vein thrombosis (DVT). Although many research studies have shown that the increased risk of clot can be due to some other additional factors rather than Tranee 500mg Injection itself. This condition has been found to be more common in female patients taking Tranee 500mg Injection. Do consult your doctor before you start this medication and follow the instructions strictly as given.
Q. Can Tranee 500mg Injection affect the colour vision of eyes?
Yes, there are chances of possible disturbances in your colour vision when you are on long term treatment with Tranee 500mg Injection. Hence, regular eye check should be done during treatment and doctor should be informed if you notice any change in your vision. If any changes are seen your doctor may stop the medicine and suggest an alternative.